Human Papillomavirus-Associated Head and Neck Cancer

被引:16
作者
Nogues, Juan C. [1 ]
Fassas, Scott [1 ]
Mulcahy, Collin [1 ]
Zapanta, Philip E. [1 ]
机构
[1] George Washington Univ, Div Otolaryngol Head & Neck Surg, Washington, DC USA
关键词
Immunization; Otolaryngology; Papillomavirus Vaccines; Patient Care Team; Primary Health Care; Sexually Transmitted Diseases; Squamous Cell Carcinoma of Head and Neck; QUALITY-OF-LIFE; OROPHARYNGEAL CANCER; UNITED-STATES; OUTCOMES; EPIDEMIOLOGY; ADOLESCENTS; CARCINOMA; SURGERY;
D O I
10.3122/jabfm.2021.04.200588
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Oropharyngeal squamous cell carcinoma (OPSCC) has historically been attributable to tobacco and alcohol exposure and saw a decline in incidence after societal norms shifted away from smoking. In recent decades, this disease has had a re-emergence due to human papillomavirus (HPV) infection, now surpassing cervical cancer as the number 1 cause of HPV-related cancer in the United States. HPV-positive OPSCC differs from HPV-negative disease in epidemiology, prognosis, treatment, and prevention. Additionally, there is a deficit in awareness of the causal relationship between HPV and OPSCC. This, coupled with low vaccination rates, puts primary care providers in a unique position to play a vital role in prevention and early diagnosis. In this review, we highlight the epidemiology, screening, patient presentation, diagnosis, prognosis, and prevention of HPV-positive OPSCC, with a focus on the primary care provider's role.
引用
收藏
页码:832 / 837
页数:6
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