Simultaneous determination of acetaminophen and ascorbic acid at an unmodified boron-doped diamond electrode by differential pulse voltammetry in buffered media

被引：58
作者：
Radovan, Ciprian [1 ]
Cofan, Codruta [2 ]
Cinghita, Dan [1 ]
机构：
[1] W Univ Timisoara, Lab Electrochem, Timisoara 300115, Romania
[2] Univ Med & Pharm Victor Babes Timisoara, Timisoara 300041, Romania
来源：
ELECTROANALYSIS | 2008年 / 20卷 / 12期
关键词：
ascorbic acid; acetaminophen; buffered media; differential pulse voltammetry; boron-doped diamond electrode;
D O I：
10.1002/elan.200804188
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A boron-doped diamond electrode (BDDE) was used for the simultaneous anodic determination Of L-ascorbic acid (AA) and acetaminophen (AC) in aqueous buffered media by differential pulse voltammetry (DPV). Linear calibration plots of anodic current peaks versus concentration were obtained for both analytes in the concentration range 0.01 - 0.1 mM with very high correlation coefficients. RSD of 2 - 3% and high sensitivities were obtained from DPV data in single and dicomponent systems. The potential applicability of the DPV technique associated with standard addition was illustrated by simultaneous determination of AA and AC in real sample solutions made up from pharmaceutical products.
引用
收藏
页码：1346 / 1353
页数：8
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