Sinonasal and sino-orbital aspergillosis in 23 cats: Aetiology, clinicopathological features and treatment outcomes

被引：53

作者：

Barrs, V. R. ^{[1
]}

Halliday, C. ^{[2
]}

Martin, P. ^{[3
]}

Wilson, B. ^{[1
]}

Krockenberger, M. ^{[3
]}

Gunew, M. ^{[4
]}

Bennett, S. ^{[5
]}

Koehlmeyer, E. ^{[6
]}

Thompson, A. ^{[7
]}

Fliegner, R. ^{[8
]}

Hocking, A. ^{[9
]}

Sleiman, S. ^{[2
]}

O'Brien, C. ^{[8
]}

Beatty, J. A. ^{[1
]}

机构：

[1] Univ Sydney, Fac Vet Sci, Valentine Charlton Cat Ctr, Sydney, NSW 2006, Australia

[2] Univ Sydney, Westmead Hosp, Ctr Infect Dis & Microbiol, Westmead, NSW 2145, Australia

[3] Univ Sydney, Fac Vet Sci, Vet Pathol Diagnost Serv, Sydney, NSW 2006, Australia

[4] Cat Clin, Mt Gravatt, Qld 4122, Australia

[5] Murdoch Univ, Dept Vet Clin Sci, Murdoch, WA 6150, Australia

[6] Anvet Beenleigh Surg, Beenleigh, Qld 4207, Australia

[7] Vet Specialist Serv, Springwood, Qld 4217, Australia

[8] Univ Melbourne, Vet Clin & Hosp, Werribee, Vic 3030, Australia

[9] CSIRO Food & Nutr Sci, N Ryde, NSW 2113, Australia

来源：

VETERINARY JOURNAL | 2012年 / 191卷 / 01期

关键词：

Aspergillosis; Aspergillus spp; Neosartorya spp; Cats; Sinonasal; Sino-orbital; CANINE NASAL ASPERGILLOSIS; ORBITAL ASPERGILLOSIS; FUNGAL RHINITIS; NEOSARTORYA-UDAGAWAE; INTRANASAL INFUSION; SINUSITIS; FUMIGATUS; CLOTRIMAZOLE; DOGS; IDENTIFICATION;

D O I：

10.1016/j.tvjl.2011.02.009

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Aetiology, clinicopathological findings and treatment outcomes were documented in 23 cats (1.5-13 years of age) with sinonasal (SNA, n = 6) or sino-orbital (SOA, n = 17) aspergillosis. Cases recruited retrospectively and prospectively were included if fungal hyphae were identified on cytological or histological examination and the fungal pathogen was identified by PCR and DNA sequencing (ITS1 or ITS1-5.8S-ITS2 regions, rDNA gene cluster). Fungal culture was positive in 22/23 cases. In cases of SNA, the fungal pathogen was Aspergillus fumigatus (n = 4), Neosartorya fischeri or A. lentulus (n = 1) or a non-speciated Neosartorya spp. (n = 1). In all cases of SOA (n = 17), the fungal pathogen was identified as Neosartorya spp. Nine cats had brachycephalic conformation. Cats with SNA were more likely to be infected with A. fumigatus and had a better prognosis than cats with SOA. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：58 / 64

页数：7

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