Functionalization of divinylbenzene/N-vinylpyrrolidone copolymer particles:: Ion exchangers for solid phase extraction

被引：29

作者：

Brousmiche, Darryl W. ^{[1
]}

O'Gara, John E. ^{[2
]}

Walsh, Daniel P. ^{[1
]}

Lee, Peter J. ^{[1
]}

Iraneta, Pamela C. ^{[1
]}

Trammell, Brian C. ^{[3
]}

Xu, Yuehong ^{[1
]}

Mallet, Claude R. ^{[1
]}

机构：

[1] Waters Corp, Milford, MA 01757 USA

[2] Boston Sci Corp, Marlborough, MA 01752 USA

[3] Patheon Pharmaceut, Cincinnati, OH 45237 USA

来源：

JOURNAL OF CHROMATOGRAPHY A | 2008年 / 1191卷 / 1-2期

关键词：

SPE; ion exchange; synthesis; recovery test;

D O I：

10.1016/j.chroma.2008.01.076

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of four-mixed mode ion exchangers for SPE, consisting of either weak or strong cation or anion exchangers, have been synthesized by functionalization of spherical, porous particles made from a copolymer of N-vinylpyrrolidone and divinylbenzene. These materials are able to selectively retain and release acidic and basic solutes through the judicious choice of wash solvent pH, as shown through the use of SPE recovery tests. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：108 / 117

页数：10

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