Core Cross-linked Polyethylene Glycol Oleate Micelles as Novel Drug Carriers

被引：0

作者：

Guo, Yanling ^{[1
]}

Wang, Baoqi ^{[2
]}

Zhao, Jun ^{[3
]}

Cui, Zhaoshan ^{[2
]}

机构：

[1] Tianjin Univ Sci & Technol, Coll Sci, Tianjin 300457, Peoples R China

[2] Tianjin Univ Sci & Technol, Coll Mat Sci & Chem Engn, Tianjin 300457, Peoples R China

[3] Hebei Univ Sci & Technol, Coll Polytech, Shijiazhuang, Hebei 050035, Peoples R China

来源：

APPLICATION OF CHEMICAL ENGINEERING, PTS 1-3 | 2011年 / 236-238卷

关键词：

Polyethylene Glycol Oleate; core cross-linked; micelles; controlled release; BLOCK-COPOLYMERS;

D O I：

10.4028/www.scientific.net/AMR.236-238.1770

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Polyethylene Glycol Oleate was synthesized by esterification of polyethylene glycol and Oil acid using DMAP as a catalyst. The double bonds of the product in the core of micelles were cross-linked by the initiation of (NH4)(2)S2O8 during the micelles formed. Applications of the noncross-linked and cross-linked polyethylene glycol oleate in drug delivery were studied, which indicates that drug efficiency decreased after micelles were core cross-linked, but release rate of MTX from core cross-linked micelles seems slower than that from noncross-linked micelles.

引用

页码：1770 / +

页数：2

共 50 条

[21] Synthesis and Characterization of Cross-linked Polyethylene Glycol/Carboxymethyl Chitosan Hydrogels
Mohamed, Riham R.
Seoudi, Rania S.
Sabaa, Magdy W.
ADVANCES IN POLYMER TECHNOLOGY, 2015, 34 (01)
[22] Morphology tailoring and temperature sensitivity control of waist cross-linked micelles and evaluation of their application as intelligent drug carriers
Yuan, Conghui
Xu, Yiting
Liao, Yifu
Lin, Sujuan
He, Ning
Dai, Lizong
JOURNAL OF MATERIALS CHEMISTRY, 2010, 20 (44) : 9968 - 9975
[23] Design of reversibly core cross-linked micelles sensitive to reductive environment
Cajot, S.
Lautram, N.
Passirani, C.
Jerome, C.
JOURNAL OF CONTROLLED RELEASE, 2011, 152 (01) : 30 - 36
[24] Synthesis of core functionalized polymer micelles and shell cross-linked nanoparticles
Ievins, Alexander D.
Wang, Xiaofan
Moughton, Adam O.
Skey, Jared
O'Reilly, Rachel K.
MACROMOLECULES, 2008, 41 (09) : 2998 - 3006
[25] Synthesis of novel shell cross-linked micelles with hydrophilic cores
Butun, V.
Armes, S.P.
2001, Oxford University Press (780):
[26] PHOTODEGRADATION OF CROSS-LINKED POLYETHYLENE
TORIKAI, A
ASADA, S
FUEKI, K
POLYMER PHOTOCHEMISTRY, 1986, 7 (01): : 1 - 11
[27] ON THE CRYSTALLIZATION OF CROSS-LINKED POLYETHYLENE
BONGARDT, J
MAY, M
PLASTE UND KAUTSCHUK, 1986, 33 (05): : 172 - 175
[28] MORPHOLOGY OF CROSS-LINKED POLYETHYLENE
不详
EPRI JOURNAL, 1983, 8 (08): : 47 - 47
[29] STABILIZATION OF CROSS-LINKED POLYETHYLENE
STENGREVICS, E
KING, RE
HOFMANN, P
POLYOLEFINS VI: SIXTH INTERNATIONAL CONFERENCE ON POLYOLEFINS, 1989, : 331 - 346
[30] Preparation of core cross-linked micelles using a photo-cross-linking agent
Kim, Jin Sook
Youk, Ji Ho
POLYMER, 2009, 50 (10) : 2204 - 2208

← 1 2 3 4 5 →