Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small Cell Lung Cancer (NSCLC)

被引：41
作者：
Doebele, R. [1 ]
Ahn, M. [2 ]
Siena, S. [3 ,4 ]
Drilon, A. [5 ]
Krebs, M. [6 ]
Lin, C. [7 ]
De Braud, F. [8 ]
John, T. [9 ]
Tan, D. [10 ]
Seto, T. [11 ]
Dziadziuszko, R. [12 ]
Arkenau, H. [13 ]
Barlesi, F. [14 ]
Rolfo, C. [15 ]
Wolf, J. [16 ]
Chow-Maneval, E. [17 ]
Multani, P. [17 ]
Cui, N. [18 ]
Riehl, T. [18 ]
Cho, B. C. [9 ]
机构：
[1] Univ Colorado, Aurora, CO USA
[2] Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Div Hematol Oncol,Dept Med, Seoul, South Korea
[3] Grande Osped Metropolitano Niguarda, Niguarda Canc Ctr, Milan, Italy
[4] Univ Milan, Milan, Italy
[5] Mem Sloan Kettering Canc Ctr, Dept Med, Div Solid Tumor Oncol, Thorac Oncol Serv, New York, NY 10021 USA
[6] Univ Manchester, Manchester, Lancs, England
[7] Natl Taiwan Univ Hosp, Dept Oncol, Taipei, Taiwan
[8] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy
[9] Yonsei Canc Ctr, Div Med Oncol, Seoul, South Korea
[10] Natl Canc Ctr, Div Med Oncol, Singapore, Singapore
[11] Natl Kyushu Canc Ctr, Dept Thorac Oncol, Fukuoka, Fukuoka, Japan
[12] Med Univ Gdansk, Dept Oncol & Radiotherapy, Gdansk, Poland
[13] Sarah Cannon Res Inst, London, England
[14] Aix Marseille Univ, AP HM, Marseille, France
[15] Antwerp Univ Hosp, Oncol Dept, Phase 1 Early Clin Trials Unit, Antwerp, Belgium
[16] Univ Hosp Cologne, Ctr Integrated Oncol Koln Bonn, Cologne, Germany
[17] Ignyta Inc, San Diego, CA USA
[18] Genentech Inc, San Francisco, CA USA
来源：
JOURNAL OF THORACIC ONCOLOGY | 2018年 / 13卷 / 10期
关键词：
NSCLC; entrectinib; ROS1 gene fusion;
D O I：
10.1016/j.jtho.2018.08.239
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OA02.01
引用
收藏
页码：S321 / S322
页数：2
相关论文
共 50 条
  • [31] Complete Response on Larotrectinib in NTRK2 Fusion-Positive Non-Small Cell Lung Cancer
    Frehner, Lorenz
    Haefliger, Simon
    Cerciello, Ferdinando
    Grob, Tobias
    Schmid, Sabine
    CASE REPORTS IN ONCOLOGY, 2023, 16 (01): : 871 - 877
  • [32] Efficacy and Safety of Pralsetinib in Chinese Patients with Advanced RET Fusion plus Non-Small Cell Lung Cancer
    Zhou, Q.
    Wu, Y.
    Chang, J.
    Wang, H.
    Fan, Y.
    Zhao, J.
    Wu, G.
    Sun, Y.
    Sun, M.
    Wang, X.
    Shi, H.
    Nian, W.
    Wang, K.
    Zheng, X.
    Qu, L.
    Yao, S.
    Shen, Z.
    Li, P.
    Yang, J.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S889 - S890
  • [33] Phase IV Study of Afatinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
    Thongprasert, Sumitra
    Boldeanu, Cosmin
    Radosavljevic, Davorin
    Petrovic, Marina
    Jones, Hilary
    Cseh, Agnieszka
    Gaafar, Rabab
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S667 - S667
  • [34] NTRK Fusion-positive Non-small-cell Lung Cancer: The Diagnosis and Targeted Therapy
    Haratake, Naoki
    Seto, Takashi
    CLINICAL LUNG CANCER, 2021, 22 (01) : 1 - 5
  • [35] Comprehensive Analysis of ROS1 Aberrations without Rearrangements in Non-small cell Lung Cancer Patients
    Glaser, M.
    Von Levetzow, C.
    Michels, S.
    Nogova, L.
    Katzenmeier, M.
    Wompner, C.
    Schmitz, J.
    Bitter, E.
    Terjung, I.
    Passmann, E.
    Schaufler, D.
    Eisert, A.
    Fischer, R.
    Riedel, R.
    Weber, J. P.
    Hahne, S.
    Merkelbach-Bruse, S.
    Buttner, R.
    Wolf, J.
    Scheffler, M.
    JOURNAL OF THORACIC ONCOLOGY, 2022, 17 (09) : S456 - S456
  • [36] Metformin Use during Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
    Wink, Krista
    Belderbos, Jose
    Dieleman, Edith
    Rossi, Maddalena
    Rasch, Coen
    Damhuis, Ronald
    Houben, Ruud
    Troost, Esther
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S278 - S279
  • [37] ROS1 Fusions Rarely Overlap with Other Oncogenic Drivers in Non-Small Cell Lung Cancer
    Lin, Jessica J.
    Ritterhouse, Lauren L.
    Ali, Siraj M.
    Bailey, Mark
    Schrock, Alexa B.
    Gainor, Justin F.
    Ferris, Lorin A.
    Mino-Kenudson, Mari
    Miller, Vincent A.
    Iafrate, Anthony J.
    Lennerz, Jochen K.
    Shaw, Alice T.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (05) : 872 - 877
  • [38] Safety and efficacy of durvalumab after concurrent chemoradiation in Black patients with locally advanced non-small cell lung cancer
    McCall, Neal S.
    Janopaul-Naylor, James R.
    McGinnis, H. Scott
    Kesarwala, Aparna H.
    Tian, Sibo
    Stokes, William A.
    Shelton, Joseph W.
    Steuer, Conor E.
    Carlisle, Jennifer W.
    Leal, Ticiana A.
    Ramalingam, Suresh S.
    Bradley, Jeffrey D.
    Higgins, Kristin A.
    CANCER, 2023, 129 (23) : 3713 - 3723
  • [39] Progress of non-small-cell lung cancer with ROS1 rearrangement
    Yang, Xin
    Tang, Zhe
    Li, Jing
    Jiang, Jizong
    Liu, Yue
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [40] Entrectinib Response to ROS1-Fusion-Positive Non-Small-Cell Lung Cancer That Progressed on Crizotinib with Leptomeningeal Metastasis: A Case Report
    Sawada, Hiromune
    Taniguchi, Yuri
    Iizuka, Shin
    Ikeda, Toshiki
    Aga, Masaharu
    Hamakawa, Yusuke
    Miyazaki, Kazuhito
    Misumi, Yuki
    Agemi, Yoko
    Nakamura, Yukiko
    Maeda, Koki
    Shimokawa, Tsuneo
    Okamoto, Hiroaki
    CASE REPORTS IN ONCOLOGY, 2023, 16 (01): : 1558 - 1567
12345