A new rearranged dolabellane diterpene from the soft coral Clavularia inflata

被引：7

作者：

Alea, Glenn V. ^{[1
]}

Bowden, Bruce F. ^{[2
]}

Ragasa, Consolacion Y. ^{[1
]}

机构：

[1] De La Salle Univ, Dept Chem, Manila 1004, Philippines

[2] James Cook Univ, Sch Pharm & Mol Sci, Douglas, Qld 4811, Australia

来源：

NATURAL PRODUCT RESEARCH | 2008年 / 22卷 / 09期

关键词：

Clavularia inflata; diterpenes; (3Z,5E,1S*,7S,12aS*)-1-isopropyl,6,12a-dimethyl-10-methylene-1,2,4,7,8,9,11,12,12a-nonahydrocyclopentacycloun decen-7-ol;

D O I：

10.1080/14786410701640528

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new dolabellane type diterpene 1 has been isolated through its acetate 1a. The structure of 1a was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by mass spectrometry. The structure of 1 was deduced by comparison of its NMR spectral data with those of 1a, while its relative stereochemistry was deduced by NOESY. The absolute stereochemistry of C-7 was determined by analyses of 1 separately esterified with R and S O-mandelic acids.

引用

页码：814 / 819

页数：6

共 11 条

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