Bioceramics: Past, present and for the future

被引：550
作者：
Best, S. M. [1 ]
Porter, A. E. [2 ]
Thian, E. S. [1 ]
Huang, J. [3 ]
机构：
[1] Univ Cambridge, Dept Mat Sci & Met, Cambridge CB2 3QZ, England
[2] Univ London Imperial Coll Sci Technol & Med, Dept Mat Sci, London SW7 2AZ, England
[3] UCL, Dept Mech Engn, London WC1E 7JE, England
来源：
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY | 2008年 / 28卷 / 07期
基金：
英国工程与自然科学研究理事会;
关键词：
apatite; glass; glass-ceramic; biomedical application; coatings;
D O I：
10.1016/j.jeurceramsoc.2007.12.001
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
There have been a number of major advances made in the field of bioactive ceramics, glasses and glass ceramics during the past 30-40 years. From initial work on the development of materials that are tolerated in the physiological environment, emphasis has now shifted towards the use of ceramic materials that interact with bone tissue by forming a direct bond. It is now possible to choose, by compositional control, whether these materials are biologically stable once incorporated within the skeletal structure or whether they are resorbed over time. This paper reviews the ground-breaking work that was performed during the 1970s and 1980s in the field of bioceramics in the production and characterisation of bioactive and bioresorbable glasses, glass ceramics and calcium phosphates. The review then explores the influence of the original concepts and ideas on the more recent development of ceramic scaffolds, composites and coatings with enhanced bioactivity for bone tissue engineering. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1319 / 1327
页数：9
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