Sertaconazole Nitrate Shows Fungicidal and Fungistatic Activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, Causative Agents of Tinea Pedis

被引：12

作者：

Carrillo-Munoz, Alfonso J. ^{[1
]}

Tur-Tur, Cristina ^{[2
]}

Cardenes, Delia C. ^{[1
]}

Estivill, Dolors ^{[3
]}

Giusiano, Gustavo ^{[4
]}

机构：

[1] ACIAM, Dept Microbiol, E-08080 Barcelona, Spain

[2] CAP Manso, SPDI, Barcelona, Spain

[3] ALTHAIA Hosp, Manresa, Spain

[4] Univ Nacl Nordeste, Reg Med Inst, Dept Micol, Resistencia, Argentina

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 09期

关键词：

VITRO ANTIFUNGAL ACTIVITY; IN-VITRO; FUNGAL-INFECTIONS; DERMATOPHYTES; BIFONAZOLE; CANDIDA; YEASTS; KETOCONAZOLE; FLUCONAZOLE; 2-PERCENT;

D O I：

10.1128/AAC.00219-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 mu g/ml, respectively, although values were higher for T. mentagrophytes than for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.

引用

页码：4420 / 4421

页数：2

共 11 条

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