Corrosion behaviour and in vitro/in vivo biocompatibility of surface-modified AZ31 alloy

被引：12

作者：

Carboneras, M. ^{[1
]}

Iglesias, C. ^{[2
]}

Perez-Maceda, B. T. ^{[3
]}

del Valle, J. A. ^{[1
]}

Garcia-Alonso, M. C. ^{[1
]}

Alobera, M. A. ^{[1
]}

Clemente, C. ^{[4
]}

Rubio, J. C. ^{[2
]}

Escudero, M. L. ^{[1
]}

Lozano, R. M. ^{[3
]}

机构：

[1] CSIC, CENIM, Madrid, Spain

[2] Hosp La Paz, Madrid, Spain

[3] CSIC, Ctr Invest Biol, Madrid, Spain

[4] Univ Alcala de Henares, Fac Med, Madrid, Spain

来源：

REVISTA DE METALURGIA | 2011年 / 47卷 / 03期

关键词：

AZ31; Magnesium fluoride; Corrosion; Biocompatibility; In vitro/in vivo; MAGNESIUM; COATINGS;

D O I：

10.3989/revmetalm.1065

中图分类号：

TF [冶金工业];

学科分类号：

0806 ;

摘要：

The present work evaluates the corrosion behaviour and the in vitro/in vivo biocompatibility of the AZ31 magnesium alloy, which fulfills the mechanical requirements of bone. The corrosion kinetic of as-received AZ31 alloy was not compatible with the cell growth. To improve its performance, the AZ31 alloy was surface modified by a chemical conversion treatment in hydrofluoric acid. The magnesium fluoride layer generated by the surface treatment of AZ31 alloy enhances its corrosion behaviour, allowing the in vitro growth of osteoblastic cells over the surface and the in vivo formation of a highly compact layer of new bone tissue. These results lead to consider the magnesium fluoride coating as necessary for potential use of the AZ31 alloy as biodegradable and absorbable implant for bone repair.

引用

页码：212 / 223

页数：12

共 18 条

[11] Metal ion release from metal implants [J].

Hanawa, T .

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2004, 24 (6-8) :745-752

[12]

LI Z, 2008, BIOMATERIALS, V29

[13]

SONG GL, 2007, CORROS SCI, V49

[14] Magnesium and its alloys as orthopedic biomaterials: A review [J].

Staiger, MP ;

Pietak, AM ;

Huadmai, J ;

Dias, G .

BIOMATERIALS, 2006, 27 (09) :1728-1734

[15] In vivo corrosion of four magnesium alloys and the associated bone response [J].

Witte, F ;

Kaese, V ;

Haferkamp, H ;

Switzer, E ;

Meyer-Lindenberg, A ;

Wirth, CJ ;

Windhagen, H .

BIOMATERIALS, 2005, 26 (17) :3557-3563

[16] Degradable biomaterials based on magnesium corrosion [J].

Witte, Frank ;

Hort, Norbert ;

Vogt, Carla ;

Cohen, Smadar ;

Kainer, Karl Ulrich ;

Willumeit, Regine ;

Feyerabend, Frank .

CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE, 2008, 12 (5-6) :63-72

[17] The design of scaffolds for use in tissue engineering. Part 1. Traditional factors [J].

Yang, SF ;

Leong, KF ;

Du, ZH ;

Chua, CK .

TISSUE ENGINEERING, 2001, 7 (06) :679-689

[18] Progress and challenge for magnesium alloys as biomaterials [J].

Zeng, Rongchang ;

Dietzel, Wolfgang ;

Witte, Frank ;

Hort, Norbert ;

Blawert, Carsten .

ADVANCED ENGINEERING MATERIALS, 2008, 10 (08) :B3-B14

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