Cross-coupling reaction of oxazoles

被引：14
作者：
Inoue, Munenori [1 ]
机构：
[1] Sagami Chem Res Ctr, Kanagawa 2521193, Japan
来源：
MINI-REVIEWS IN ORGANIC CHEMISTRY | 2008年 / 5卷 / 02期
关键词：
oxazoles; cross-coupling; Negishi reaction; Stille reaction; Suzuki-Miyaura reaction; Sonogashira reaction;
D O I：
10.2174/157019308784223596
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The metal-catalyzed cross-coupling reaction of oxazoles is discussed in this review. Initially, preparation of metallated oxazoles (oxazole-M) and halo-and trifloyloxazoles (oxazole-X) is outlined. After that, comprehensive examples of Negishi, Stille, Suzuki-Miyaura, and Sonogashira reactions at each three position in oxazoles (C-2, C-4, and C-5) are detailed with showing both types of reactions [route A (reaction of oxazol-M and Ar-X) and route B (reaction of oxazole-X and Ar-M)].
引用
收藏
页码：77 / 84
页数：8
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