Neuronal activity during development: permissive or instructive?

被引：148
作者：
Crair, MC
机构：
[1] Baylor Coll Med, Div Neurosci, Houston, TX 77030 USA
[2] Baylor Coll Med, Program Dev Biol, Houston, TX 77030 USA
来源：
CURRENT OPINION IN NEUROBIOLOGY | 1999年 / 9卷 / 01期
关键词：
D O I：
10.1016/S0959-4388(99)80011-7
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Experimental studies over the past year have shown that neural activity has a range of effects on the development of neural pathways. Although activity appears unimportant for establishing many aspects of the gross morphology and topology of the brain, there are many cases where the presence of neural activity is essential for the formation of a mature system of neural connections; in some instances, the pattern of neural activity actually orchestrates the final arrangement of neural connections.
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页码：88 / 93
页数：6
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