Brief Report on 3-Weekly Paclitaxel Carboplatin Efficacy in Locally Advanced or Metastatic Squamous Vulvar Cancer

被引：12

作者：

Amant, Frederic ^{[1
,2
,3
]}

Nooij, Linda ^{[1
]}

Annibali, Daniela ^{[2
,3
]}

van Rompuy, Anne-Sophie ^{[4
]}

Han, Sileny ^{[5
]}

van den Bulck, Heidi ^{[6
,7
]}

Goffin, Frederic ^{[8
]}

机构：

[1] Netherlands Canc Inst, Antoni van Leeuwenhoek, Ctr Gynecol Oncol, Dept Gynecol Oncol, Amsterdam, Netherlands

[2] Katholieke Univ Leuven, Dept Oncol, Leuven, Belgium

[3] Univ Hosp Leuven, Dept Obstet Gynecol, Leuven, Belgium

[4] Univ Hosp Leuven, Dept Pathol, Leuven, Belgium

[5] Univ Hosp Leuven, Dept Obstet Gynecol, Leuven, Belgium

[6] Univ Hosp Leuven, Dept Med Oncol, Leuven, Belgium

[7] Imelda Hosp, Dept Med Oncol, Bonheiden, Belgium

[8] Hosp la Citadelle, Dept Obstet Gynecol, Liege, Belgium

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 2018年 / 83卷 / 06期

关键词：

Advanced vulvar cancer; Neoadjuvant chemotherapy; Treatment; Chemoradiation; NEOADJUVANT CHEMOTHERAPY; CELL CARCINOMA; MANAGEMENT; RECURRENT; SURGERY;

D O I：

10.1159/000487435

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In this brief report, we present our experience with 3-weekly paclitaxel-carboplatin chemotherapy for patients with vulvar cancer. Two patients with locally advanced disease had an impressive response allowing standard vulvar cancer surgery. One patient with metastatic disease had local stable disease though it was progressive in the lymph nodes. The available literature is sparse and retrospective. Based on promising results, however, a prospective multi-center study is mandatory in order to obtain full data in a larger series of patients in order to learn the benefits of neo-adjuvant paclitaxel-carboplatin and compare the results with chemoradiation. (c) 2018 S. Karger AG, Basel

引用

页码：620 / 626

页数：7

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