Long-term mortality and cardiovascular outcomes in patients with atrial flutter after catheter ablation

被引：8

作者：

Yugo, Dony ^{[1
,2
]}

Chen, Yun-Yu ^{[1
,3
,4
]}

Lin, Yenn-Jiang ^{[1
,5
,6
,7
,8
]}

Chien, Kuo-Liong ^{[3
,4
]}

Chang, Shih-Lin ^{[1
,5
,6
,7
,8
]}

Lo, Li-Wei ^{[1
,5
,6
,7
,8
]}

Hu, Yu-Feng ^{[1
,5
,6
,7
,8
]}

Chao, Tze-Fan ^{[1
,5
,6
,7
,8
]}

Chung, Fa-Po ^{[1
,5
,6
,7
,8
]}

Liao, Jo-Nan ^{[1
,5
,6
,7
,8
]}

Chang, Ting-Yung ^{[1
,5
,6
,7
,8
]}

Lin, Chin-Yu ^{[1
,5
,6
,7
,8
]}

Tuan, Ta-Chuan ^{[1
]}

Kuo, Ling ^{[1
]}

Wu, Cheng-, I ^{[1
,5
,6
,7
,8
]}

Liu, Chih-Min ^{[1
,5
,6
,7
,8
]}

Liu, Shin-Huei ^{[1
]}

Li, Cheng-Hung ^{[5
,6
,7
,8
,9
]}

Hsieh, Yu-Cheng ^{[5
,6
,7
,8
,9
]}

Chen, Shih-Ann ^{[1
,5
,6
,7
,8
,9
]}

机构：

[1] Taipei Vet Gen Hosp, Heart Rhythm Ctr, Taipei, Taiwan

[2] Univ Indonesia, Fac Med, Cardiovasc Dept, Jakarta, Indonesia

[3] Natl Taiwan Univ, Inst Epidemiol, Taipei, Taiwan

[4] Natl Taiwan Univ, Prevent Med Coll Publ Hlth, Taipei, Taiwan

[5] Natl Yang Ming Chiao Tung Univ, Fac Med, Taipei, Taiwan

[6] Natl Yang Ming Chiao Tung Univ, Fac Med, Hsinchu, Taiwan

[7] Natl Yang Ming Chiao Tung Univ, Inst Clin Med, Taipei, Taiwan

[8] Natl Yang Ming Chiao Tung Univ, Inst Clin Med, Hsinchu, Taiwan

[9] Taichung Vet Gen Hosp, Cardiovasc Ctr, Taichung, Taiwan

来源：

EUROPACE | 2022年 / 24卷 / 06期

基金：

芬兰科学院;

关键词：

Atrial fibrillation; Atrial flutter; Ablation; Cardiovascular outcome; FIBRILLATION; RISK; STROKE;

D O I：

10.1093/europace/euab308

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims For patients with typical and atypical atrial flutter (AFL) but without history of atrial fibrillation (AF), the long-term cardiovascular (CV) outcomes after catheter ablation for AFL remain unclear. We compared the long-term all-cause mortality and CV outcomes in patients with AFL receiving catheter ablation compared with the results with medical therapy. Methods and results Atrial flutter patients receiving catheter ablation for typical AFL were identified using the Health Insurance Database, and constituted the 'AFL ablation group'. Patients with typical and atypical AFL but without ablation (AFL without ablation group) were propensity matched to the AFL ablation group. Patients with prior AF diagnosis were excluded. Primary outcomes included all-cause and CV mortality, heart failure (HF) hospitalization, and stroke. The multivariable cox hazards regression model was used to evaluate the hazard ratio (HR) for study outcomes. A total of 3784 AFL patients (1892 patients in each group) was studied. Their mean follow-up durations were 7.85 +/- 2.57 years (AFL without ablation group) and 8.31 +/- 4.53 years (AFL ablation group). Atrial flutter with ablation patients had lower risks of all-cause mortality (HR: 0.68, P < 0.001), CV deaths (HR: 0.78, P = 0.001), HF hospitalization (HR: 0.84, P = 0.01), and stroke (HR: 0.80, P = 0.01). Conclusions Catheter ablation for AFL in patients without prior AF was associated with lower risks of all-cause mortality and CV events compared with AFL patients without ablation during long-term follow-ups.

引用

页码：970 / 978

页数：9