Efficient synthesis of benzocyclotrimer analogues by Negishi cross-coupling and intramolecular nucleophilic substitution

被引：5

作者：

Borges-Gonzalez, Jorge ^{[1
]}

Martin, Tomas ^{[1
,2
]}

机构：

[1] CSIC, Inst Prod Nat & Agrobiol, Avda Astrofis Francisco Sanchez 3, San Cristobal la Laguna 38206, Sc De Tenerife, Spain

[2] Inst Univ Bioorgan Antonio Gonzalez, CIBICAN, Avda Astrofis Francisco Sanchez 2, San Cristobal la Laguna 38206, Sc De Tenerife, Spain

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 04期

关键词：

GUEST BINDING; MOLECULAR RECOGNITION; RECEPTORS; COOPERATIVITY; AFFINITY; BASKETS; BENZENE; DESIGN; HOST;

D O I：

10.1039/c7cc08616d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a new and efficient synthetic strategy that allows access to flexible and functionalized benzocyclotrimers under mild conditions and in few steps. The Negishi cross-coupling reaction was used for the C-C bond formation, whereas intramolecular O-alkylations provided the oxepane rings.

引用

页码：362 / 365

页数：4

共 25 条

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