Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

被引:250
作者
Ley, R [1 ]
Ewings, KE [1 ]
Hadfield, K [1 ]
Cook, SJ [1 ]
机构
[1] Babraham Inst, Mol Signalling Lab, Cambridge CB2 4AT, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/sj.cdd.4401688
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:1008 / 1014
页数:7
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共 57 条
  • [1] Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA
    Abrams, MT
    Robertson, NM
    Yoon, K
    Wickstrom, E
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (53) : 55809 - 55817
  • [2] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms
    Adachi, M
    Zhao, X
    Imai, K
    [J]. CELL DEATH AND DIFFERENTIATION, 2005, 12 (02) : 192 - 193
  • [3] Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim
    Akiyama, T
    Bouillet, P
    Miyazaki, T
    Kadono, Y
    Chikuda, H
    Chung, UG
    Fukuda, A
    Hikita, A
    Seto, H
    Okada, T
    Inaba, T
    Sanjay, A
    Baron, R
    Kawaguchi, H
    Oda, H
    Nakamura, K
    Strasser, A
    Tanaka, S
    [J]. EMBO JOURNAL, 2003, 22 (24) : 6653 - 6664
  • [4] The specificities of protein kinase inhibitors: an update
    Bain, J
    McLauchlan, H
    Elliott, M
    Cohen, P
    [J]. BIOCHEMICAL JOURNAL, 2003, 371 : 199 - 204
  • [5] Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein
    Barbar, E
    Kleinman, B
    Imhoff, D
    Li, MG
    Hays, TS
    Hare, M
    [J]. BIOCHEMISTRY, 2001, 40 (06) : 1596 - 1605
  • [6] Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
    Becker, EBE
    Howell, J
    Kodama, Y
    Barker, PA
    Bonni, A
    [J]. JOURNAL OF NEUROSCIENCE, 2004, 24 (40) : 8762 - 8770
  • [7] Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation
    Biswas, SC
    Greene, LA
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (51) : 49511 - 49516
  • [8] Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist bim
    Bouillet, P
    Cory, S
    Zhang, LC
    Strasser, A
    Adams, JM
    [J]. DEVELOPMENTAL CELL, 2001, 1 (05) : 645 - 653
  • [9] Proapoptotic Bcl-2 relative bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    Bouillet, P
    Metcalf, D
    Huang, DCS
    Tarlinton, DM
    Kay, TWH
    Köntgen, F
    Adams, JM
    Strasser, A
    [J]. SCIENCE, 1999, 286 (5445) : 1735 - 1738
  • [10] BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    Bouillet, P
    Purton, JF
    Godfrey, DI
    Zhang, LC
    Coultas, L
    Puthalakath, H
    Pellegrini, M
    Cory, S
    Adams, JM
    Strasser, A
    [J]. NATURE, 2002, 415 (6874) : 922 - 926