Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

被引：251
作者：
Ley, R [1 ]
Ewings, KE [1 ]
Hadfield, K [1 ]
Cook, SJ [1 ]
机构：
[1] Babraham Inst, Mol Signalling Lab, Cambridge CB2 4AT, England
来源：
CELL DEATH AND DIFFERENTIATION | 2005年 / 12卷 / 08期
基金：
英国生物技术与生命科学研究理事会;
关键词：
D O I：
10.1038/sj.cdd.4401688
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：1008 / 1014
页数：7
相关论文
共 57 条
[1]   Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA [J].
Abrams, MT ;
Robertson, NM ;
Yoon, K ;
Wickstrom, E .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (53) :55809-55817
[2]   Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms [J].
Adachi, M ;
Zhao, X ;
Imai, K .
CELL DEATH AND DIFFERENTIATION, 2005, 12 (02) :192-193
[3]   Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim [J].
Akiyama, T ;
Bouillet, P ;
Miyazaki, T ;
Kadono, Y ;
Chikuda, H ;
Chung, UG ;
Fukuda, A ;
Hikita, A ;
Seto, H ;
Okada, T ;
Inaba, T ;
Sanjay, A ;
Baron, R ;
Kawaguchi, H ;
Oda, H ;
Nakamura, K ;
Strasser, A ;
Tanaka, S .
EMBO JOURNAL, 2003, 22 (24) :6653-6664
[4]   The specificities of protein kinase inhibitors: an update [J].
Bain, J ;
McLauchlan, H ;
Elliott, M ;
Cohen, P .
BIOCHEMICAL JOURNAL, 2003, 371 :199-204
[5]   Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein [J].
Barbar, E ;
Kleinman, B ;
Imhoff, D ;
Li, MG ;
Hays, TS ;
Hare, M .
BIOCHEMISTRY, 2001, 40 (06) :1596-1605
[6]   Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis [J].
Becker, EBE ;
Howell, J ;
Kodama, Y ;
Barker, PA ;
Bonni, A .
JOURNAL OF NEUROSCIENCE, 2004, 24 (40) :8762-8770
[7]   Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation [J].
Biswas, SC ;
Greene, LA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (51) :49511-49516
[8]   Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist bim [J].
Bouillet, P ;
Cory, S ;
Zhang, LC ;
Strasser, A ;
Adams, JM .
DEVELOPMENTAL CELL, 2001, 1 (05) :645-653
[9]   Proapoptotic Bcl-2 relative bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity [J].
Bouillet, P ;
Metcalf, D ;
Huang, DCS ;
Tarlinton, DM ;
Kay, TWH ;
Köntgen, F ;
Adams, JM ;
Strasser, A .
SCIENCE, 1999, 286 (5445) :1735-1738
[10]   BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes [J].
Bouillet, P ;
Purton, JF ;
Godfrey, DI ;
Zhang, LC ;
Coultas, L ;
Puthalakath, H ;
Pellegrini, M ;
Cory, S ;
Adams, JM ;
Strasser, A .
NATURE, 2002, 415 (6874) :922-926
123456