Prediction of the Spatial Resolution of Magnetic Particle Imaging Using the Modulation Transfer Function of the Imaging Process

被引：84

作者：

Knopp, Tobias ^{[1
]}

Biederer, Sven ^{[1
]}

Sattel, Timo F. ^{[1
]}

Erbe, Marlitt ^{[1
]}

Buzug, Thorsten M. ^{[1
]}

机构：

[1] Univ Lubeck, Inst Med Engn, D-23562 Lubeck, Germany

来源：

IEEE TRANSACTIONS ON MEDICAL IMAGING | 2011年 / 30卷 / 06期

关键词：

Deconvolution; full-width at half-maximum (FWHM); magnetic particle imaging (MPI); modulation transfer function (MTF); reconstruction; spatial resolution; RECONSTRUCTION; SIGNAL;

D O I：

10.1109/TMI.2011.2113188

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

The magnetic particle imaging method allows for the quantitative determination of spatial distributions of superparamagnetic nanoparticles in vivo. Recently, it was shown that the 1-D magnetic particle imaging process can be formulated as a convolution. Analyzing the width of the convolution kernel allows for predicting the spatial resolution of the method. However, this measure does not take into account the noise of the measured data. Furthermore, it does not consider a reconstruction step, which can increase the resolution beyond the width of the convolution kernel. In this paper, the spatial resolution of magnetic particle imaging is investigated by analyzing the modulation transfer function of the imaging process. An expression for the spatial resolution is derived, which includes the noise level and which is validated in simulations and experiments.

引用

页码：1284 / 1292

页数：9

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