Inhibitory activities of aromatic amino acid esters and peptides against ovalbumin permeation through Caco-2 cell monolayers

被引：5
|
作者：
Kobayashi, S [1 ]
Watanabe, J
机构：
[1] Takasaki Univ Hlth & Welf, Dept Food & Life Sci, Takasaki, Gumma 3700033, Japan
[2] Natl Food Res Inst, Food Funct Div, Tsukuba, Ibaraki 3058642, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2003年 / 67卷 / 11期
关键词：
allergen absorption; Caco-2; aromatic amino acid ethyl ester; aromatic amino acid dipeptide;
D O I：
10.1271/bbb.67.2498
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Trp, Phe, and Tyr ethyl esters and their dipeptides with Gly at the C-terminals inhibited ovalbumin (OVA) permeation through Caco-2 monolayers. The inhibitory activity of Trp ethyl ester was the highest at near the concentration of 10(-6) M. It was suggested that Trp ethyl ester inhibited transcellular permeation of OVA.
引用
收藏
页码：2498 / 2500
页数：3
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