Coeliac Disease: Background and biochemical aspects

被引：37
作者：
Hamer, RJ [1 ]
机构：
[1] WUR Wageningen, Ctr Prot Technol, Wageningen, Netherlands
[2] TNO Qual Life, Zeist, Netherlands
来源：
BIOTECHNOLOGY ADVANCES | 2005年 / 23卷 / 06期
关键词：
coeliac disease; gluten; peptides;
D O I：
10.1016/j.biotechadv.2005.05.005
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Coeliac Disease has to be considered a main food related affliction, with life long consequences for the people having the disease. Coeliac Disease patients suffer from adverse effects that can be related to specific gluten peptide sequences that trigger a sequence of immune related reactions leading to damage of the intestine and related malabsorption symptoms. Recently, detailed information has come available on peptide sequences that are toxic for Coeliac Disease patients. This information is discussed in relation to prevention of the disease and the development of safe cereals for Coeliac Disease patients. (C) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码：401 / 408
页数：8
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