Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England

被引:30
|
作者
Campbell, Helen E. [1 ]
Stokes, Elizabeth A. [1 ]
Bargo, Danielle N. [2 ]
Curry, Nicola [3 ]
Lecky, Fiona E. [4 ]
Edwards, Antoinette [4 ]
Woodford, Maralyn [4 ]
Seeney, Frances [5 ]
Eaglestone, Simon [6 ]
Brohi, Karim [6 ]
Gray, Alastair M. [1 ]
Stanworth, Simon J. [7 ,8 ]
机构
[1] Univ Oxford, Hlth Econ Res Ctr, Nuffield Dept Populat Hlth, Oxford OX3 7LF, England
[2] Eli Lilly & Co Ltd, Basingstoke RG24 9NL, Hants, England
[3] Churchill Hosp, Oxford Univ Hosp NHS Trust, Oxford Haemophilia & Thrombosis Ctr, Oxford OX3 7LE, England
[4] Salford Royal NHS Fdn Trust, Trauma Audit & Res Network, Salford M6 8HD, Lancs, England
[5] NHS Blood & Transplant Clin Trials Unit, Bristol BS34 8RR, Avon, England
[6] Barts & London Queen Marys Sch Med & Dent, Blizard Inst, London E1 2AT, England
[7] John Radcliffe Hosp, NHS Blood & Transplant, Oxford OX3 9BQ, England
[8] John Radcliffe Hosp, Oxford Univ Hosp NHS Trust, Oxford OX3 9BQ, England
来源
CRITICAL CARE | 2015年 / 19卷
关键词
MASSIVE TRANSFUSION; ECONOMIC-EVALUATION; BLUNT TRAUMA; WALES; BLOOD; COAGULOPATHY; MANAGEMENT; OUTCOMES; TRIAL;
D O I
10.1186/s13054-015-0987-5
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Severely bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions. Methods: In collaboration with the Trauma Audit Research Network (TARN) detailed patient-level data on in-hospital resource use, extended care at hospital discharge, and readmissions up to 12 months post-injury were collected on 441 consecutive adult major trauma patients with severe bleeding presenting at 22 hospitals (21 in England and one in Wales). Resource use data were costed using national unit costs and mean costs estimated for the cohort and for clinically relevant subgroups. Using nationally available data on trauma presentations in England, patient-level cost estimates were up-scaled to a national level. Results: The mean (95 % confidence interval) total cost of initial hospital inpatient care was 19,770 pound (18,177 pound to 21,364) pound per patient, of which 62 % was attributable to ventilation, intensive care, and ward stays, 16 % to surgery, and 12 % to blood component transfusion. Nursing home and rehabilitation unit care and re-admissions to hospital increased the cost to 20,591 pound (18,924 pound to 22,257) pound. Costs were significantly higher for more severely injured trauma patients (Injury Severity Score >= 15) and those with blunt injuries. Cost estimates for England were 148,300,000 pound, with over a third of this cost attributable to patients aged 65 years and over. Conclusions: Severely bleeding major trauma patients are a high cost subgroup of all major trauma patients, and the cost burden is projected to rise further as a consequence of an aging population and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios. The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/ or treatment practice can begin to be evaluated. Further studies are still required to determine the full costs of post-discharge care requirements, which are also likely to be substantial.
引用
收藏
页数:14
相关论文
共 50 条
  • [31] Spine injuries among severely injured trauma patients: A retrospective single-center cohort study
    Lassila, Henri
    Heinanen, Mikko
    Serlo, Joni
    Brinck, Tuomas
    SCANDINAVIAN JOURNAL OF SURGERY, 2024, 113 (04) : 293 - 302
  • [32] Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: A prospective observational study of 404 severely injured patients
    Ostrowski, Sisse R.
    Henriksen, Hanne H.
    Stensballe, Jakob
    Gybel-Brask, Mikkel
    Cardenas, Jessica C.
    Baer, Lisa A.
    Cotton, Bryan A.
    Holcomb, John B.
    Wade, Charles E.
    Johansson, Par I.
    JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2017, 82 (02): : 293 - 301
  • [33] Improving the care of patients with severe open fractures of the tibia THE EFFECT OF THE INTRODUCTION OF MAJOR TRAUMA NETWORKS AND NATIONAL GUIDELINES
    Wordsworth, M.
    Lawton, G.
    Nathwani, D.
    Pearse, M.
    Naique, S.
    Dodds, A.
    Donaldson, H.
    Bhattacharya, R.
    Jain, A.
    Simmons, J.
    Hettiaratchy, S.
    BONE & JOINT JOURNAL, 2016, 98B (03): : 420 - 424
  • [34] Vertebral artery injury in major trauma patients in Saudi Arabia: A retrospective cohort study
    Chowdhury, Sharfuddin
    Almubarak, Sadiq Hussain
    Binsaad, Khadega Hadi
    Mitra, Biswadev
    Fitzgerald, Mark
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [35] Postprocedural Complications Hospitalization Pattern Among Paediatric Patients at National Health Service Trusts: An Ecological Study in England and Wales
    Naser, Abdallah Y.
    Al-shehri, Hassan
    JOURNAL OF MULTIDISCIPLINARY HEALTHCARE, 2023, 16 : 3545 - 3554
  • [36] Healthcare Costs of Not Achieving Remission in Patients with Rheumatoid Arthritis in the United States: A Retrospective Cohort Study
    Bergman, Martin
    Zhou, Lili
    Patel, Pankaj
    Sawant, Ruta
    Clewell, Jerry
    Tundia, Namita
    ADVANCES IN THERAPY, 2021, 38 (05) : 2558 - 2570
  • [37] Implementation of Trauma Center and Massive Transfusion Protocol Improves Outcomes for Major Trauma Patients: A Study at a Single Institution in Korea
    Hwang, Kyungjin
    Kwon, Junsik
    Cho, Jayun
    Heo, Yunjung
    Lee, John Cook-Jong
    Jung, Kyoungwon
    WORLD JOURNAL OF SURGERY, 2018, 42 (07) : 2067 - 2075
  • [38] Does Antithrombotic Therapy Affect Outcomes in Major Trauma Patients? A Retrospective Cohort Study from a Tertiary Trauma Centre
    Sartini, Stefano
    Spadaro, Marzia
    Cutuli, Ombretta
    Castellani, Luca
    Sartini, Marina
    Cristina, Maria Luisa
    Canepa, Paolo
    Tognoni, Chiara
    Lo, Agnese
    Canata, Lorenzo
    Rosso, Martina
    Arboscello, Eleonora
    JOURNAL OF CLINICAL MEDICINE, 2022, 11 (19)
  • [39] Evaluation of healthcare costs and utilization for patients with gout: a population-based matched cohort study
    Lee, Yi-Yun
    Tang, Chao-Hsiun
    Chen, Jin-Hua
    Kuo, Li-Na
    Ko, Yu
    CURRENT MEDICAL RESEARCH AND OPINION, 2018, 34 (04) : 735 - 740
  • [40] Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study
    Serrier, Hassan
    Rabier, Hugo
    Fernandez, Violaine
    Schott, Anne -Marie
    Mewton, Nathan
    Ovize, Michel
    Nighoghossian, Norbert
    Duclos, Antoine
    Colin, Cyrille
    JOURNAL OF CARDIOLOGY, 2024, 83 (01) : 44 - 48