Vitamin D status in osteoporotic postmenopausal women taking oral recommended vitamin D supplementation

被引:6
|
作者
Ivorra, Jose [1 ]
Valls, Elia [2 ,3 ]
Fernandez-Llanio Cornelia, Nagore [1 ]
Chalmeta Verdejo, Inmaculada [1 ]
Oliver Oliver, Maria Jesus [4 ]
Roman Ivorra, Jose Andres [2 ,3 ]
机构
[1] Hosp Univ Dr Peset, Serv Reumatol, Valencia, Spain
[2] Hosp Politecn, Serv Reumatol, Valencia, Spain
[3] Univ La Fe, Valencia, Spain
[4] Hosp Univ Dr Peset, Lab Anal Clin, Secc Hormonas, Valencia, Spain
来源
MEDICINA CLINICA | 2012年 / 138卷 / 05期
关键词
Vitamin D; Cholecalciferol; Dietary supplements; Effectiveness; HEALTH;
D O I
10.1016/j.medcli.2011.07.024
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and objective: To assess the effectiveness of currently recommended daily intakes of vitamin D (25[OH ]D) to bring optimal serum concentrations (30 ng/ml) in postmenopausal osteoporotic women. Patients and methods: We reviewed 25(OH)D serum concentrations in 165 consecutive osteoporotic postmenopausal women who were taking oral vitamin D daily supplements above 800 IU during at least 3 months. The proportion of patients who achieved 25(OH)D levels of 20, 30 and 40 ng/ml were compared according to daily vitamin D intakes (group 1: 800-1,000 IU, group 2:1,001-1.600 IU, group 3:> 1,600 IU). Results: Mean patient age was 69 (10) years. Percentage of patients with serum 25(OH)D levels above 20 ng/ml was 79.5% (63.5-88.5%), 92.7%(78.7-96%) and 97.6% (90.6-100%) in group 1, 2, and 3 patients, respectively (P=.009). Serum levels above 30 ng/ml were achieveJ in 27.7% (14.7-44.7%), 53.6% (37.670%) and 90.2% (81.2-96.6%), respectively (P <.001). Serum levels above 40 ng/ml were reached in 7.2% (1-20%), 24.4% (12-40%) and 61% (49-72%), respectively (P <.001). Conclusion: Daily reference intakes of vitamin D supplements (800-1,0001U) may be insufficient to achieve optimal serum levels of vitamin D in postmenopausal ostceoporotic women. (C) 2011 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码:199 / 201
页数:3
相关论文
共 50 条
  • [31] Inadequate vitamin D status in pregnancy: evidence for supplementation
    Finer, Sarah
    Khan, Khalid S.
    Hitman, Graham A.
    Griffiths, Chris
    Martineau, Adrian
    Meads, Catherine
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2012, 91 (02) : 159 - 163
  • [32] Vitamin D status and supplementation in pediatric gastrointestinal disease
    O'Malley, Tarah
    Heuberger, Roschelle
    JOURNAL FOR SPECIALISTS IN PEDIATRIC NURSING, 2011, 16 (02) : 140 - 150
  • [33] Vitamin D Status and Supplementation in Elite Irish Athletes
    Magee, Pamela J.
    Pourshahidi, L. Kirsty
    Wallace, Julie M. W.
    Cleary, John
    Conway, Joe
    Harney, Edward
    Madigan, Sharon M.
    INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 2013, 23 (05) : 441 - 448
  • [34] Vitamin D Status, Parathyroid Function, Bone Turnover, and BMD in Postmenopausal Women With Osteoporosis: Global Perspective
    Kuchuk, Natalia O.
    van Schoor, Natasja M.
    Pluijm, Saskia M.
    Chines, Arkadi
    Lips, Paul
    JOURNAL OF BONE AND MINERAL RESEARCH, 2009, 24 (04) : 693 - 701
  • [35] Nutritional Status of Vitamin D and the Effect of Vitamin D Supplementation in Korean Breast-fed Infants
    Kim, Mi-Jung
    Na, Bomi
    No, So-Jung
    Han, Heon-Seok
    Jeong, Eun-Hwan
    Lee, Wonkuk
    Han, Younghee
    Hyeun, Taisun
    JOURNAL OF KOREAN MEDICAL SCIENCE, 2010, 25 (01) : 83 - 89
  • [36] Necessity of daily 1000-IU vitamin D supplementation for maintaining a sufficient vitamin D status
    Ikezumi, Yuya
    Matsuura, Yasushi
    Morishita, Teruhiro
    Ide, Noriko
    Kitada, Isao
    Katayama, Takafumi
    Tsutsumi, Rie
    Sakaue, Hiroshi
    Taketani, Yutaka
    Sairyo, Koichi
    Takeda, Eiji
    JOURNAL OF MEDICAL INVESTIGATION, 2022, 69 (1-2): : 135 - 140
  • [37] Effects of vitamin D supplementation on pulmonary function in postmenopausal women following an aquatic exercise program
    Nolasco, Rodrigo
    Moreira, Linda D. F.
    Bocalini, Danilo S.
    Fronza, Fernanda C. A. O.
    Marin, Rosangela Villa
    Lazaretti-Castro, Marise
    ARCHIVES OF ENDOCRINOLOGY METABOLISM, 2017, 61 (01): : 28 - 35
  • [38] Effects of High-Dose Vitamin D Supplementation on Placental Vitamin D Metabolism and Neonatal Vitamin D Status
    Vestergaard, Anna Louise
    Andersen, Matilde Kanstrup
    Andersen, Helena Hordum
    Bossow, Krista Agathe
    Bor, Pinar
    Larsen, Agnete
    NUTRIENTS, 2024, 16 (13)
  • [39] Vitamin D deficiency in postmenopausal Egyptian women
    Ragab, Wael S.
    Saleh, Wael F.
    Tawfik, Lamia T.
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2013, 123 (01) : 75 - 76
  • [40] Vitamin D supplementation - is it only osteoprotection?
    Frankiewicz, Tadeusz
    PRZEGLAD MENOPAUZALNY, 2011, 10 (04): : 328 - 333