(CAG)n loci as genetic modifiers of age-at-onset in patients with Machado-Joseph disease from mainland China

被引：35

作者：

Chen, Zhao ^{[1
]}

Zheng, Caifa ^{[1
]}

Long, Zhe ^{[1
]}

Cao, Li ^{[2
,3
]}

Li, Xunhua ^{[4
]}

Shang, Huifang ^{[5
]}

Yin, Xinzhen ^{[6
]}

Zhang, Baorong ^{[6
]}

Liu, Jingyu ^{[7
]}

Ding, Dongxue ^{[1
]}

Peng, Yun ^{[1
]}

Wang, Chunrong ^{[1
]}

Peng, Huirong ^{[1
]}

Ye, Wei ^{[1
]}

Qiu, Rong ^{[8
]}

Pan, Qian ^{[9
]}

Xia, Kun ^{[9
]}

Chen, Shengdi ^{[2
,3
]}

Sequeiros, Jorge ^{[10
,11
,12
]}

Ashizawa, Tetsuo ^{[13
,14
]}

Klockgether, Thomas ^{[15
]}

Tang, Beisha ^{[1
,9
,16
]}

Jiang, Hong ^{[1
,9
,16
,17
]}

机构：

[1] Cent S Univ, Dept Neurol, Xiangya Hosp, Changsha 410008, Hunan, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Dept Neurol, Shanghai 200025, Peoples R China

[3] Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Inst Neurol, Shanghai 200025, Peoples R China

[4] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurol, Guangzhou 510080, Guangdong, Peoples R China

[5] Sichuan Univ, West China Hosp, Dept Neurol, Chengdu 610041, Sichuan, Peoples R China

[6] Zhejiang Univ, Sch Med, Dept Neurol, Affiliated Hosp 2, Hangzhou 310009, Zhejiang, Peoples R China

[7] Huazhong Univ Sci & Technol, Ctr Human Genome Res, Coll Life Sci & Technol, Key Lab Mol Biophys,Minist Educ, Wuhan 430074, Hubei, Peoples R China

[8] Cent S Univ, Sch Informat Sci & Engn, Changsha 410083, Hunan, Peoples R China

[9] Cent S Univ, State Key Lab Med Genet, Changsha 410078, Hunan, Peoples R China

[10] Univ Porto, IBMC Inst Mol & Cell Biol, Rua Campo Alegre 823, P-4100 Oporto, Portugal

[11] Univ Porto, Inst Invest & Inovacao Saude I3S, Rua Campo Alegre 823, P-4100 Oporto, Portugal

[12] Univ Porto, ICBAS, Rua Campo Alegre 823, P-4100 Oporto, Portugal

[13] Univ Florida, Dept Neurol, Gainesville, FL USA

[14] Univ Florida, McKnight Brain Inst, Gainesville, FL USA

[15] Univ Hosp Bonn, Dept Neurol, Bonn, Germany

[16] Cent S Univ, Key Lab Hunan Prov Neurodegenerat Disorders, Changsha 410008, Hunan, Peoples R China

[17] Xinjiang Med Univ, Xinjiang 830011, Peoples R China

来源：

BRAIN | 2016年 / 139卷

关键词：

PATHOGENESIS; ATAXIA;

D O I：

10.1093/brain/aww087

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页数：5