Statins in the treatment of autosomal dominant polycystic kidney disease

被引:6
作者
Ecder, Tevfik [1 ]
机构
[1] Istanbul Bilim Univ, Div Nephrol, Dept Internal Med, Fac Med, Istanbul, Turkey
关键词
REDUCTASE INHIBITORS; ENDOTHELIAL FUNCTION; RENAL-FUNCTION; LOVASTATIN; SIMVASTATIN; PRAVASTATIN;
D O I
10.1093/ndt/gfv449
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
aEuro broken vertical bar Will statins take a place in the therapeutic armamentarium of ADPKD? We need large randomized controlled trials to give a clear answer to this question. Until we get this evidence, the decision to use a statin in the management of patients with ADPKD will remain with the physician.aEuro broken vertical bar.
引用
收藏
页码:1194 / 1196
页数:3
相关论文
共 22 条
[1]   From Finland to Fatland: Beneficial effects of statins for patients with chronic kidney disease [J].
Afzali, B ;
Haydar, AA ;
Vinen, K ;
Goldsmith, DJA .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2004, 15 (08) :2161-2168
[2]   Beneficial effects of statins on the kidney: the evidence moves from mouse to man [J].
Afzali, B ;
Haydar, AA ;
Vinen, K ;
Goldsmith, DJA .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 (05) :1032-1036
[3]   Statins-beyond lipids in CKD [J].
Amann, Kerstin ;
Benz, Kerstin .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2011, 26 (02) :407-410
[4]   Effect of Pravastatin on Total Kidney Volume, Left Ventricular Mass Index, and Microalbuminuria in Pediatric Autosomal Dominant Polycystic Kidney Disease [J].
Cadnapaphornchai, Melissa A. ;
George, Diana M. ;
McFann, Kim ;
Wang, Wei ;
Gitomer, Berenice ;
Strain, John D. ;
Schrier, Robert W. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 9 (05) :889-896
[5]   Statin therapy improves brachial artery endothelial function in nephrotic syndrome [J].
Dogra, GK ;
Watts, GF ;
Herrmann, S ;
Thomas, MAB ;
Irish, AB .
KIDNEY INTERNATIONAL, 2002, 62 (02) :550-557
[6]   Cardiovascular Complications in Autosomal Dominant Polycystic Kidney Disease [J].
Ecder, Tevfik .
CURRENT HYPERTENSION REVIEWS, 2013, 9 (01) :2-11
[7]   Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on renal function [J].
Epstein, M ;
Campese, VM .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2005, 45 (01) :2-14
[8]   Effect of pravastatin on kidney function and urinary protein excretion in autosomal dominant polycystic kidney disease [J].
Fassett, Robert G. ;
Coombes, Jeff S. ;
Packham, David ;
Fairley, Kenneth F. ;
Kincaid-Smith, Priscilla .
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, 2010, 44 (01) :56-61
[9]   EFFECT OF LOVASTATIN ON THE DEVELOPMENT OF POLYCYSTIC KIDNEY-DISEASE IN THE HAN-SPRD RAT [J].
GILE, RD ;
COWLEY, BD ;
GATTONE, VH ;
ODONNELL, MP ;
SWAN, SK ;
GRANTHAM, JJ .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1995, 26 (03) :501-507
[10]   Renal microcirculatory effects of lovastatin in a rat model of reduced renal mass [J].
Glazer, AA ;
Inman, SR ;
Stowe, NT ;
Novick, AC .
UROLOGY, 1997, 50 (05) :812-817