10α-Hydroxy-4,9-dimethyl-13-[(4-phenylpiperazin-1-yl)methyl]-3,8,15-trioxatetracyclo[10.3.0.02,4.07,9]tetradecan-14-one

被引：1

作者：

Moumou, Mohamed ^{[2
]}

Benharref, Ahmed ^{[2
]}

Oudahmane, Abdelghani ^{[3
]}

Elhakmaoui, Ahmed ^{[1
]}

Berraho, Moha ^{[2
]}

机构：

[1] Univ Hassan 2, Chim Bioorgan & Analyt Lab, FSTM, Mohammedia Casablanca 20810, Mohammedia, Morocco

[2] Fac Sci Semlalia, Lab Chim Biomol Subst Nat & Reactivite, Marrakech 40000, Morocco

[3] Univ Clermont Ferrand, Lab Mat Inorgan, CNRS, UMR 6002, F-63177 Aubiere, France

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷

关键词：

GERMACRANOLIDES;

D O I：

10.1107/S1600536811042012

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C25H34N2O5, was synthesized from 9 alpha-hydroxyparthenolide (9 alpha-hydroxy-4,8-dimethyl-12-methylene-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one), which was isolated from the chloroform extract of the aerial parts of Anvillea radiata. The molecule contains a fused five-and ten-membered ring system. The ten-membered ring adopts an approximate chair-chair conformation, while the five-membered ring is in an envelope conformation, with the C atom closest to the hydroxy group forming the flap. The piperazine ring is in a chair conformation. In the crystal, O-H center dot center dot center dot O hydrogen bonds connect molecules into chains along [100]. Weak intermolecular C-H center dot center dot center dot O hydrogen bonds are also present.

引用

页码：O2981 / U903

页数：12