Association of Polygenic Risk Score With Blood Pressure and Adverse Cardiovascular Outcomes in Individuals With Type II Diabetes: Insights From the ACCORD Trial

被引：1

作者：

Parcha, Vibhu ^{[1
]}

Pampana, Akhil ^{[1
]}

Bress, Adam P. ^{[3
]}

Irvin, Marguerite R. ^{[2
]}

Arora, Garima ^{[1
]}

Arora, Pankaj ^{[1
,4
]}

机构：

[1] Univ Alabama Birmingham, Div Cardiovasc Dis, 1670 Univ Blvd,Volker Hall B140, Birmingham, AL 35294 USA

[2] Univ Alabama Birmingham, Sch Publ Hlth, Dept Epidemiol, Birmingham, AL 35294 USA

[3] Univ Utah, Sch Med, Dept Populat Hlth Sci, Salt Lake City, UT USA

[4] Birmingham Vet Affairs Med Ctr, Sect Cardiol, Birmingham, AL USA

来源：

HYPERTENSION | 2022年 / 79卷 / 05期

基金：

美国国家卫生研究院;

关键词：

blood pressure; cardiovascular disease; diabetes mellitus; genomics; genotype; hypertension;

D O I：

10.1161/HYPERTENSIONAHA.122.18976

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

引用

页码：E100 / E102

页数：3

共 5 条

[1] 10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2021 [J].

不详 .

DIABETES CARE, 2021, 44 :S125-S150

[2] Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits [J].

Evangelou, Evangelos ;

Warren, Helen R. ;

Mosen-Ansorena, David ;

Mifsu, Borbala ;

Pazoki, Raha ;

Gao, He ;

Ntritsos, Georgios ;

Dimou, Niki ;

Cabrer, Claudia P. ;

Karaman, Ibrahim ;

Ng, FuLiang ;

Evangelou, Marina ;

Witkowska, Katarzyna ;

Tzanis, Evan ;

Hellwege, Jacklyn N. ;

Giri, Ayush ;

Edwards, Digna R. Velez ;

Sun, Yan, V ;

Cho, Kelly ;

Gaziano, J. Michael ;

Wilson, Peter W. F. ;

Tsao, Philip S. ;

Kovesdy, Csaba P. ;

Esko, Tonu ;

Magi, Reedik ;

Milani, Lili ;

Almgren, Peter ;

Boutin, Thibaud ;

Debette, Stephanie ;

Ding, Jun ;

Giulianini, Franco ;

Holliday, Elizabeth G. ;

Jackson, Anne U. ;

Li-Gao, Ruifang ;

Lin, Wei-Yu ;

Luan, Jian'an ;

Mangino, Massimo ;

Oldmeadow, Christopher ;

Prins, Bram Peter ;

Qian, Yong ;

Sargurupremraj, Muralidharan ;

Shah, Nabi ;

Surendran, Praveen ;

Theriault, Sebastien ;

Verweij, Niek ;

Willems, Sara M. ;

Zhao, Jing-Hua ;

Amouyel, Philippe ;

Connell, John ;

de Mutsert, Renee .

NATURE GENETICS, 2018, 50 (10) :1412-+

[3]

Gerstein HC, 2008, NEW ENGL J MED, V358, P2545, DOI 10.1056/NEJMoa0802743

[4] Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial [J].

Morieri, Mario Luca ;

Gao, He ;

Pigeyre, Marie ;

Shah, Hetal S. ;

Sjaarda, Jennifer ;

Mendonca, Christine ;

Hastings, Timothy ;

Buranasupkajorn, Patinut ;

Motsinger-Reif, Alison A. ;

Rotroff, Daniel M. ;

Sigal, Ronald J. ;

Marcovina, Santica M. ;

Kraft, Peter ;

Buse, John B. ;

Wagner, Michael J. ;

Gerstein, Hertzel C. ;

Mychaleckyj, Josyf C. ;

Pare, Guillaume ;

Doria, Alessandro .

DIABETES CARE, 2018, 41 (11) :2404-2413

[5] Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure [J].

Tobin, MD ;

Sheehan, NA ;

Scurrah, KJ ;

Burton, PR .

STATISTICS IN MEDICINE, 2005, 24 (19) :2911-2935

← 1 →