The blink reflex and the corneal reflex are followed by cortical activity resembling the nociceptive potentials induced by trigeminal laser stimulation in man

被引：2

作者：

de Tommaso, M

Libro, G

Guido, M

Sciruicchio, V

Puca, F

机构：

[1] Interuniv Ctr Study Headache & Neurotransmitter D, Perugia, Italy

[2] Interuniv Ctr Study Headache & Neurotransmitter D, Rome, Italy

[3] Interuniv Ctr Study Headache & Neurotransmitter D, Sassari, Italy

[4] Interuniv Ctr Study Headache & Neurotransmitter D, Bari, Italy

[5] Interuniv Ctr Study Headache & Neurotransmitter D, Naples, Italy

[6] Interuniv Ctr Study Headache & Neurotransmitter D, Florence, Italy

来源：

NEUROSCIENCE LETTERS | 2001年 / 310卷 / 01期

关键词：

blink reflex; corneal reflex; laser stimulation; pain-related potentials;

D O I：

10.1016/S0304-3940(01)02086-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Laser stimulation of the supraorbital regions evokes brain potentials (LEPs) related to trigeminal nociception. The aim of this study was to record the R2 component of the blink reflex and the corneal reflex in 20 normal subjects, comparing the scalp activity following these reflexes with the nociceptive potentials evoked by CO2 laser stimulation of supraorbital regions. Cortical and muscular reflexes evoked by stimulation of the first trigeminal branch were recorded simultaneously. The R2 component of the blink reflex and the corneal reflex were followed by two cortical peaks, which resembled morphologically N-P waves of LEPs. The two peaks demonstrated a difference in latency of approximately 40 ms, which is consistent with activation time of nociception. This finding suggests that these reflexes are induced by activation of small pain-related fibers. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：37 / 40

页数：4