Synthesis and characterization of thermo- and pH-sensitive hydrogels based on Chitosan-grafted N-isopropylacrylamide via γ-radiation

被引：65
|
作者：
Cai, H
Zhang, ZP [1 ]
Sun, PC
He, BL
Zhu, XX
机构：
[1] State Key Lab Funct Polymer Mat Adsorpt & Separat, Tianjin 300071, Peoples R China
[2] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada
来源：
RADIATION PHYSICS AND CHEMISTRY | 2005年 / 74卷 / 01期
关键词：
chitosan; N-isopropylacrylamide; thermo- and pH-sensitive; graft; gamma-radiation;
D O I：
10.1016/j.radphyschem.2004.10.007
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Thermo- and pH-sensitive hydrogels were prepared by graft copolymerization of chitosan (CS) and N-isopropylacrylamide via gamma-radiation. The effects of monomer concentration and irradiation dose on grafting percentage and grafting efficiency were studied. The graft copolymers were characterized by C-13 CP/MAS NMR and thermogravimetric analysis. The pH and thermosensitivity and swelling properties of the hydrogels were investigated. The results showed that the grafting percentage and grafting efficiency increased with the increase of monomer concentration and total irradiation dose. The highest grafting percentage is 620%, the lower critical solution temperature (LCST) of this hydrogel is about 28 degrees C. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：26 / 30
页数：5
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