Beryllium-associated diseases from a chemist's point of view

被引：40
作者：
Buchner, Magnus R. [1 ]
机构：
[1] Philipps Univ Marburg, Fachbereich Chem, Nachwuchsgrp Berylliumchem, Anorgan Chem, Hans Meerwein Str 4, Marburg 35032, Germany
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2020年 / 75卷 / 05期
关键词：
beryllium; berylliosis; bioinorganic chemistry; chronic beryllium disease; CD4(+) T-CELLS; CRYSTAL-STRUCTURE; HLA-DP; X-RAY; AQUEOUS-SOLUTION; BINDING; COORDINATION; IDENTIFICATION; COMPLEXES; HLA-DP2;
D O I：
10.1515/znb-2020-0006
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Beryllium has long been considered the most toxic non-radioactive element to humans. However, it is shown that the acute toxicity of beryllium ions does not exceed that of other toxic cations like Cd2+, Ba2+, Hg2+ or As3+. The physiological mechanisms liable for the development of beryllium-associated diseases are discussed. Additionally an overview over proposed low-molecular model system for the beryllium species responsible for beryllioses is presented.
引用
收藏
页码：405 / 412
页数：8
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