Methotrexate-induced hepatic necrosis requiring liver transplantation in a patient with rheumatoid arthritis

被引：0

作者：

Hakim, NS ^{[1
]}

Kobienia, B ^{[1
]}

Benedetti, E ^{[1
]}

Bloomer, J ^{[1
]}

Payne, WD ^{[1
]}

机构：

[1] Univ Minnesota, Dept Surg, Minneapolis, MN 55455 USA

来源：

INTERNATIONAL SURGERY | 1998年 / 83卷 / 03期

关键词：

liver transplantation; methotrexate; hepatic necrosis; rheumatoid arthritis;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

MTX-induced hepatic injury and liver enzyme elevations have been demonstrated after treatment of leukemia, gestational disease and during treatment of psoriasis and rheumatoid arthritis. A 40-year-old man with a long standing history of rheumatoid arthritis was treated with MTX over a 6 month period and developed an overwhelming hepatic necrosis. He was successfully transplanted.

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页码：224 / 225

页数：2

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