Molecularly imprinted polymer integrated plasmonic nanosensor for cocaine detection

被引:13
作者
Ozgur, Erdogan [1 ,2 ]
Saylan, Yeseren [1 ]
Bereli, Nilay [1 ]
Turkmen, Deniz [1 ]
Denizli, Adil [1 ]
机构
[1] Hacettepe Univ, Dept Chem, TR-06800 Ankara, Turkey
[2] Hacettepe Univ, Adv Technol Applicat & Res Ctr, Ankara, Turkey
关键词
Cocaine detection; molecularly imprinted polymer; nanofilm; plasmonic nanosensor; METABOLITES; NANOPARTICLES; RECOGNITION; EXTRACTION; SAMPLES; URINE;
D O I
10.1080/09205063.2020.1751524
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A molecularly imprinted polymeric nanofilm was prepared for cocaine detection and applied to plasmonic nanosensor for real-time kinetic, selectivity and reusability analyses. The sensing polymeric surface was fabricated by synthesizing a selective and specific nanofilm on the gold plasmonic nanosensor surface. After characterization experiments with atomic force microscopy, ellipsometer, and contact angle measurements, the kinetic studies of cocaine detection in aqueous solutions in a wide concentration range between 0.2-100 mu g/mL were applied to plasmonic nanosensor system at 24 degrees C with a low limit of detection (0.1 mu g/L) and quantification values (0.3 mu g/L) and the results showed that this molecularly imprinted polymeric nanofilm integrated plasmonic nanosensor is providing a model for the fastest, most accurate and most precise identification of the cocaine molecule which constitutes a large part of the workload of forensic laboratories.
引用
收藏
页码:1211 / 1222
页数:12
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