Sorafenib Reduced Significantly Heptopulmonary Shunt in a Large Hepatocelullar Carcinoma

被引：4

作者：

d'Abadie, Philippe ^{[1
]}

Borbath, Ivan ^{[2
]}

Goffette, Pierre ^{[3
]}

Amini, Nadia ^{[3
]}

Lhommel, Renaud ^{[1
]}

机构：

[1] Catholic Univ Louvain, Clin Univ St Luc, Dept Nucl Med, Ave Hippocrate 10, B-1200 Brussels, Belgium

[2] Catholic Univ Louvain, Clin Univ St Luc, Dept Gastroenterol, Brussels, Belgium

[3] Catholic Univ Louvain, Clin Univ St Luc, Dept Intervent Radiol, Brussels, Belgium

来源：

CLINICAL NUCLEAR MEDICINE | 2019年 / 44卷 / 01期

关键词：

radioembolization; hepatocellular carcinoma; sorafenib; RADIOEMBOLIZATION; Y-90;

D O I：

10.1097/RLU.0000000000002369

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

An 81-year-old man with a large hepatocellular carcinoma was referred in our institution for Y-90 radioembolization (RE). The preliminary arteriography using Tc-99m-macroaggregate albumin demonstrated an important hepatopulmonary shunt. It was an exclusion criterion for RE due to high risks of lung radiations. Then, the patient was treated with sorafenib during 4 months, stopped because of grade 3 toxicity. A second liver arteriography was performed, and Tc-99m-macroaggregate albumin imaging showed an important reduction of the lung shunt. Transient therapy with sorafenib permitted to close the lung shunt and was a bridge for RE.

引用

页码：70 / 71

页数：2

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