IgG4-Related Pleural Disease Diagnosed by a Re-Evaluation of Chronic Bilateral Pleuritis in a Patient Who Experienced Occasional Acute Left Bacterial Pleuritis

被引：32

作者：

Yamamoto, Hiroshi ^{[1
]}

Suzuki, Toshiro ^{[1
]}

Yasuo, Masanori ^{[1
]}

Kobayashi, Orie ^{[1
]}

Tsushima, Kenji ^{[1
]}

Ito, Michiko ^{[1
]}

Urushihata, Kazuhisa ^{[1
]}

Yamazaki, Yoshitaka ^{[1
]}

Hanaoka, Masayuki ^{[1
]}

Koizumi, Tomonobu ^{[1
]}

Uehara, Takeshi ^{[2
]}

Kawakami, Satoshi ^{[3
]}

Hamano, Hideaki ^{[4
]}

Kawa, Shigeyuki ^{[5
]}

Kubo, Keishi ^{[1
]}

机构：

[1] Shinshu Univ, Sch Med, Dept Internal Med 1, Matsumoto, Nagano, Japan

[2] Shinshu Univ, Sch Med, Dept Pathol, Matsumoto, Nagano, Japan

[3] Shinshu Univ, Sch Med, Dept Radiol, Matsumoto, Nagano, Japan

[4] Shinshu Univ, Sch Med, Dept Internal Med 2, Matsumoto, Nagano, Japan

[5] Shinshu Univ, Sch Med, Ctr Hlth Safety & Environm Management, Matsumoto, Nagano, Japan

来源：

INTERNAL MEDICINE | 2011年 / 50卷 / 08期

关键词：

pleuritis; lymphoplasmacytic; IgG4; pleuroscopy; AUTOIMMUNE PANCREATITIS; INVOLVEMENT; FIBROSIS; EFFUSION; CELLS; LUNG;

D O I：

10.2169/internalmedicine.50.4726

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 78-year-old man with cryptogenic chronic bilateral lymphoplasmacytic pleuritis, diagnosed based on left parietal pleural biopsy specimens obtained by pleuroscopy, developed acute left bacterial pleuritis. The left pleural effusion was neutrophil dominant, however, the right pleural effusion showed lymphoplasmacytic infiltration. Laboratory examinations revealed that his serum IgG4 concentration was increased, with a higher level of IgG4 in the right pleural effusion. Re-evaluation of the previous biopsy specimens using an immunostaining method revealed numerous IgG4-positive plasma cell infiltrations with IgG4-positive/IgG-positive plasma cells at 85.4%. Accordingly, the new diagnosis of this patient was considered to be chronic bilateral IgG4-related pleuritis.

引用

页码：893 / 897

页数：5

共 11 条

[11] IgG4-related Lung and Pleural Disease: A Clinicopathologic Study of 21 Cases [J].

Zen, Yoh ;

Inoue, Dai ;

Kitao, Azusa ;

Onodera, Manabu ;

Abo, Hitoshi ;

Miyayama, Shiro ;

Gabata, Toshifumi ;

Matsui, Osamu ;

Nakanuma, Yasuni .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2009, 33 (12) :1886-1893

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