Nasal Smooth Muscle Hamartoma in a Dog: a Novel Subtype

被引:0
|
作者
von Stade, Devin [1 ]
Kawalilak, Lukas [2 ]
Worley, Deanna R. [3 ,4 ]
Andrie, Kendra M. [1 ]
Aboellail, Tawfik [1 ]
Schaffer, Paula A. [1 ]
机构
[1] Colorado State Univ, Dept Microbiol Immunol & Pathol, Ft Collins, CO 80523 USA
[2] Pulse Vet Specialists & Emergency, Sherwood Pk, AB, Canada
[3] Colorado State Univ, Dept Clin Sci, Ft Collins, CO 80523 USA
[4] Flint Anim Canc Ctr, Ft Collins, CO USA
关键词
dog; hamartoma; immunohistochemistry; nasal cavity; ANGIOLEIOMYOMA;
D O I
10.1016/j.jcpa.2021.05.005
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A 3-year-old, female spayed, Pug-cross dog presented with a 2-year history of nasal congestion and focal facial deformity. Complete surgical excision was elected following nasopharyngoscopy, endoscopic biopsy and sub-sequent computed tomography (CT) scan. Nasopharyngoscopy revealed a friable, polypoid mass of the right nasal conchae occluding the right nasal passage. Biopsies of the mass showed expansion of the submucosa by dense bundles of well-differentiated smooth muscle cells that were strongly immunoreactive for alpha-smooth muscle actin and desmin. Post-procedure CT revealed a large space-occupying mass in the nasal cavity with minimal lysis of the adjacent calvarium. Histology following complete excision confirmed the results obtained on the initial endoscopic biopsy. The final diagnosis was smooth muscle hamartoma. (C) 2021 Elsevier Ltd. All rights reserved.
引用
收藏
页码:31 / 34
页数:4
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