Lateral skull base surgery for posterior oral cavity cancer

被引:3
作者
Ren, Z-H [1 ,2 ,3 ]
Yang, Z-M [1 ,4 ]
Fan, T-F [1 ]
Wu, H-J [1 ]
机构
[1] Cent South Univ, Dept Oral & Maxillofacial Surg, Xiangya Hosp 2, 139 Renmin Rd, Changsha 410011, Hunan, Peoples R China
[2] Hainan Western Cent Hosp, Dept Oral & Maxillofacial Surg, Danzhou, Hainan, Peoples R China
[3] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Oral & Maxillofacial & Head & Neck Oncol, Sch Med, Shanghai, Peoples R China
[4] Guilin Med Univ, Dept Oral & Maxillofacial Surg, Affiliated Hosp, Guilin, Guangxi Zhuang, Peoples R China
关键词
mouth neoplasms; surgical oncology; retrospective studies; cancer survivors; prognosis; SQUAMOUS-CELL CARCINOMA; BUCCAL MUCOSA; TUMOR; STATISTICS; EXPERIENCE; RESECTION; OUTCOMES; SUBSITE; NECK; HEAD;
D O I
10.1016/j.ijom.2021.03.011
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this study was to better understand posterior oral cavity cancer (POCC) and its surgical treatment. This was a retrospective study of 76 patients who were diagnosed with POCC and underwent surgical treatment. Twenty-eight patients were treated with anatomical unit resection surgery (AURS) and 48 patients with conventional surgery. After initial treatment with curative intent, the patients were followed-up regularly with clinical examinations and imaging; the median duration of follow-up was 30.9 months (range 2-67 months). The 3-year overall survival was 64.3% in the experimental AURS group and 39.6% in the conventional surgery control group (hazard ratio 0.49, 95% confidence interval 0.26-0.93; P = 0.031). The 3-year disease-free survival was 64.3% in the experimental group and 37.5% in the control group (hazard ratio 0.53, 95% confidence interval 0.27-1.02; P = 0.114). In conclusion, AURS is an effective surgical treatment for POCC that can considerably improve patient survival rates.
引用
收藏
页码:143 / 151
页数:9
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