Synthesis of the 2α-benzoylamido analogue of docetaxel

被引：10

作者：

Fang, WS ^{[1
]}

Fang, QC

Liang, XT

机构：

[1] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 07期

关键词：

paclitaxel; docetaxel; 2-benzoylamido analogue of docetaxel; S(N)2 double inversion;

D O I：

10.1016/S0040-4039(00)02243-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 2 alpha -benzoylamido analogue of docetaxel 2 was synthesized with a double inversion of the C-2 configuration as the key step, and its cytotoxic activity towards three tumor cell lines was tested. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1331 / 1333

页数：3

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