Rat retinal progenitor cells and a retinal pigment epithelial factor

被引：8

作者：

Sheedlo, HJ ^{[1
]}

Brun-Zinkernagel, AM ^{[1
]}

Oakford, LX ^{[1
]}

Roque, RS ^{[1
]}

机构：

[1] Univ N Texas, Hlth Sci Ctr, Dept Anat & Pathol, Div Cell Biol & Genet, Ft Worth, TX 76107 USA

来源：

DEVELOPMENTAL BRAIN RESEARCH | 2001年 / 127卷 / 02期

关键词：

nestin; opsin; reverse transcriptase-polymerase chain reaction; retina; progenitor cell; retinal pigment epithelium;

D O I：

10.1016/S0165-3806(01)00118-3

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor. The isolated progenitor cells demonstrated nuclei with abundant euchromatin typical of progenitor cells and showed the presence of nestin and opsin message. A protein (similar to 67 kDa) isolated from conditioned media of cultured rat RPE cells promoted the survival of isolated retinal progenitor cells. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：185 / 187

页数：3

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