Syntheses of Some Thiazolidin-4-ones as Potential Antimicrobial Agents

被引：0
|
作者：
Havaldar, Freddy H. [1 ]
Sharma, Azad Kumar S. [1 ]
机构：
[1] St Xaviers Coll, Nadkarny Sacasa Res Lab, Dept Chem, Bombay 400001, Maharashtra, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2011年 / 23卷 / 03期
关键词：
Synthesis; Thiazolidin-4-ones; Antibacterial and antifungal activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
4-Acetamido-2-methoxybenzoyl hydrazine (1) on condensation with different aromatic aldehydes yielded the substituted benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazines (2a-f) which on cyclization with thioglycolic acid in presence of anhydrous aluminium chloride as catalyst afforded 2-(substituted phenyl)-3-(4'-acetamido-2.-methoxy benzamido)-5-H-thiazolidin-4-ones (3a-f). The structures of the newly synthesized compounds have been established by analytical and spectral methods. These compounds have also been screened for their biological activity.
引用
收藏
页码：1314 / 1316
页数：3
相关论文
共 50 条
  • [41] Synthesis of Thiazolidin-4-ones from Substituted (Ylidene)hydrazinecarbothioamides and Dimethyl Acetylenedicarboxylate
    Hassan, Alaa A.
    Aly, Ashraf A.
    El-Shaieb, Kamal M. A.
    Bedair, Tarek M. I.
    Braese, Stefan
    Brown, Alan B.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (03) : 674 - 682
  • [42] Synthesis of new functionalized thiazolidin-4-ones by the condensation of thioureas with dialkyl acetylenedicarboxylates
    Streltsov, Andrey A.
    Izmest'ev, Alexei N.
    Strelenko, Yurii A.
    Kravchenko, Angelina N.
    Gazieva, Galina A.
    MENDELEEV COMMUNICATIONS, 2024, 34 (04) : 563 - 565
  • [43] Regioseiective synthesis, structure and behavior in solutions of novel phosphorylated thiazolidin-4-ones
    Kozlov, VA
    Odinets, IL
    Lyssenko, KA
    Churusova, SG
    Yarovenko, SV
    Petrovskii, PV
    Mastryukova, TA
    HETEROATOM CHEMISTRY, 2005, 16 (02) : 159 - 168
  • [44] Synthesis of novel thiazolidin-4-ones by reaction of malonthioamide derivatives with dimethyl acetylenedicarboxylate
    Berseneva, VS
    Tkachev, AV
    Morzherin, YY
    Dehaen, W
    Luyten, I
    Toppet, S
    Bakulev, VA
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1998, (14): : 2133 - 2136
  • [45] Annulative Coupling of β-Ketosulfoxonium Ylides and β-Ketothioamides: Access to Thiazolines and Thiazolidin-4-Ones
    Saini, Rahul Kumar
    Pandey, Satyendra Kumar
    ADVANCED SYNTHESIS & CATALYSIS, 2024, 366 (19) : 4073 - 4077
  • [46] Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells
    Isloor, Arun M.
    Sunil, Dhanya
    Shetty, Prakash
    Malladi, Shridhar
    Pai, K. S. R.
    Maliyakkl, Naseer
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (02) : 758 - 767
  • [47] A convenient and efficient synthesis of thiazolidin-4-ones via cyclization of substituted hydrazinecarbothioamides
    Hassan, Alaa A.
    Mohamed, Nasr K.
    El-Shaieb, Kamal M. A.
    Tawfeek, Hendawy N.
    Braese, Stefan
    Nieger, Martin
    ARABIAN JOURNAL OF CHEMISTRY, 2019, 12 (02) : 289 - 294
  • [48] In silico Approach to Identify Novel Thiazolidin-4-ones Against Staphylococcus aureus
    Srikala, Rajala
    Mohanalakshmi, S.
    ASIAN JOURNAL OF PHARMACEUTICS, 2022, 16 (04) : 414 - 422
  • [49] Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells
    Arun M. Isloor
    Dhanya Sunil
    Prakash Shetty
    Shridhar Malladi
    K. S. R. Pai
    Naseer Maliyakkl
    Medicinal Chemistry Research, 2013, 22 : 758 - 767
  • [50] Novel Thiazolidin-4-ones as Potential Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase
    Petrou, Anthi
    Eleftheriou, Phaedra
    Geronikaki, Athina
    Akrivou, Melpomeni G.
    Vizirianakis, Ioannis
    MOLECULES, 2019, 24 (21):
12345