A case of imported COVID-19 diagnosed by PCR-positive lower respiratory specimen but with PCR-negative throat swabs

被引:42
作者
Hase, Ryota [1 ,2 ]
Kurita, Takashi [1 ]
Muranaka, Emiri [1 ,2 ]
Sasazawa, Hiroki [1 ,2 ]
Mito, Haruki [1 ]
Yano, Yudai [1 ]
机构
[1] Japanese Red Cross Narita Hosp, Dept Infect Dis, Chiba, Japan
[2] Kameda Med Ctr, Dept Infect Dis, Chiba, Japan
关键词
Coronavirus disease 2019 (COVID-19); the novel corona virus (SARS-CoV-2); real-time reverse transcription-polymerase chain reaction (RT-PCR) assay;
D O I
10.1080/23744235.2020.1744711
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A 35-year-old woman presented with fever and mild diarrhoea without any respiratory symptoms 9 days after travelling to Japan from Wuhan, China. Her computed tomography scan revealed pneumonia. The first polymerase chain reaction (PCR) test on throat swab for the novel corona virus upon admission was negative. Therefore, she was treated for community-acquired pneumonia, but fever persisted. On hospital day 5, PCR test on induced sputum was positive, but a second polymerase chain reaction test on throat swab remained negative. She was discharged, fully recovered, on hospital day 12. A lower respiratory tract specimen should be obtained for better diagnosis of corona virus disease 2019, even in the absence of respiratory symptoms for patients with significant travel or exposure history.
引用
收藏
页码:423 / 426
页数:4
相关论文
共 9 条
  • [1] [Anonymous], INT GUID CLIN MAN SE
  • [2] Centers for Disease Control and Prevention, INT GUID COLL HANDL
  • [3] Huang CL, 2020, LANCET, V395, P497, DOI [10.1016/S0140-6736(20)30183-5, 10.1016/S0140-6736(20)30211-7]
  • [4] Importance of Specimen Type and Quality in Diagnosing Middle East Respiratory Syndrome
    Huh, Hee Jae
    Ko, Jae-Noon
    Kim, Young-Eun
    Park, Chang-Hun
    Hong, Geehay
    Choi, Rihwa
    Yu, Shinae
    Cho, Sun Young
    Kang, Ji-Man
    Lee, Myoung-Keun
    Ki, Chang-Seok
    Kang, Eun-Suk
    Lee, Nam Yong
    Kim, Jong-Won
    Kim, Yae-Jean
    Ha, Young Eun
    Kang, Cheol-In
    Chung, Doo Ryeon
    Peck, Kyong Ran
    Song, Jae-Hoon
    [J]. ANNALS OF LABORATORY MEDICINE, 2017, 37 (01) : 81 - 83
  • [5] Respiratory Tract Samples, Viral Load, and Genome Fraction Yield in Patients With Middle East Respiratory Syndrome
    Memish, Ziad A.
    Al-Tawfiq, Jaffar A.
    Makhdoom, Hatem Q.
    Assiri, Abdullah
    Alhakeem, Raafat F.
    Albarrak, Ali
    Alsubaie, Sarah
    Al-Rabeeah, Abdullah A.
    Hajomar, Waleed H.
    Hussain, Raheela
    Kheyami, Ali M.
    Almutairi, Abdullah
    Azhar, Esam I.
    Drosten, Christian
    Watson, Simon J.
    Kellam, Paul
    Cotten, Matthew
    Zumla, Alimuddin
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2014, 210 (10) : 1590 - 1594
  • [6] Development of Genetic Diagnostic Methods for Detection for Novel Coronavirus 2019(nCoV-2019) in Japan
    Shirato, Kazuya
    Nao, Naganori
    Katano, Harutaka
    Takayama, Ikuyo
    Saito, Shinji
    Kato, Fumihiro
    Katoh, Hiroshi
    Sakata, Masafumi
    Nakatsu, Yuichiro
    Mori, Yoshio
    Kageyama, Tsutomu
    Matsuyama, Shutoku
    Takeda, Makoto
    [J]. JAPANESE JOURNAL OF INFECTIOUS DISEASES, 2020, 73 (04) : 304 - 307
  • [7] Tang P, 2004, CAN MED ASSOC J, V170, P47
  • [8] Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China
    Wang, Dawei
    Hu, Bo
    Hu, Chang
    Zhu, Fangfang
    Liu, Xing
    Zhang, Jing
    Wang, Binbin
    Xiang, Hui
    Cheng, Zhenshun
    Xiong, Yong
    Zhao, Yan
    Li, Yirong
    Wang, Xinghuan
    Peng, Zhiyong
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (11): : 1061 - 1069
  • [9] *WHO, 37 WHO