Reproductive problems and intensity of anxiety and depression in women treated for infertility

Aim. The aim of the study was to assess the severity of anxiety and depression in women treated for infertility as compared to the severity of these clinical parameters in women without reproductive problems, and to assess the impact of emotional disorders on the ovulation cycle. Method. Ovulation was assessed by hormonal and ultrasound examinations. The emotional state was examined by the STAI Anxiety State and Trait Inventory and the HADS anxiety and depression scale. Results. The severity of anxiety as a trait and as a state according to STAI was significantly higher in women treated for infertility than in women with confirmed fertility, as well as higher in women treated for infertility who did not get pregnant than in those who got pregnant. The severity of anxiety and depression were significantly higher in women treated for infertility than in women with confirmed fertility. Women treated for infertility who did not become pregnant had higher severity of depressive symptoms compared to women who were pregnant. In the serum of women treated for infertility, cortisol levels, both during and after ovulation, positively correlated with the severity of anxiety and depression. The same correlations were found in the group of women with confirmed fertility. Conclusions. (1) Anxiety and depression are associated with human reproductive problems. The nature and direction of the association is to be explored. (2) Emotional disorders adversely affect the secretion of sex cycle hormones and endometrial growth. (3) Couples with reproductive problems require psychological support to improve the effects of infertility treatment.