Molecular cloning, phylogenetic analysis and heat shock response of Babesia gibsoni heat shock protein 90

被引：4

作者：

Yamasaki, Masahiro ^{[1
]}

Tsuboi, Yoshihiro ^{[2
]}

Taniyama, Yusuke ^{[2
]}

Uchida, Naohiro ^{[1
]}

Sato, Reeko ^{[1
]}

Nakamura, Kensuke ^{[3
]}

Ohta, Hiroshi ^{[2
]}

Takiguchi, Mitsuyoshi ^{[2
]}

机构：

[1] Iwate Univ, Fac Agr, Dept Vet Med, Lab Vet Small Anim Internal Med, 3-18-8 Ueda, Morioka, Iwate 0208550, Japan

[2] Hokkaido Univ, Grad Sch Vet Med, Dept Vet Clin Sci, Lab Vet Internal Med, Sapporo, Hokkaido 0600818, Japan

[3] Hokkaido Univ, Grad Sch Vet Med, Vet Teaching Hosp, Sapporo, Hokkaido 0600818, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2016年 / 78卷 / 08期

关键词：

Babesia gibsoni; heat shock protein 90; phylogenetic analysis; STAGE DIFFERENTIATION; IN-VITRO; HSP90; HEAT-SHOCK-PROTEIN-90; SEQUENCE; GROWTH; IDENTIFICATION; EXPRESSION; PATHWAYS; ISOFORMS;

D O I：

10.1292/jvms.16-0027

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The Babesia gibsoni heat shock protein 90 (BgHSP90) gene was cloned and sequenced. The length of the gene was 2,610 bp with two introns. This gene was amplified from cDNA corresponding to full length coding sequence (CDS) with an open reading frame of 2,148 bp. A phylogenetic analysis of the CDS of HSP90 gene showed that B. gibsoni was most closely related to B. bovis and Babesia sp. BQ1/Lintan and lies within a phylogenetic cluster of protozoa. Moreover, mRNA transcription profile for BgHSP90 exposed to high temperature were examined by quantitative real-time reverse transcription-polymerase chain reaction. BgHSP90 levels were elevated when the parasites were incubated at 43 degrees C for 1 hr.

引用

页码：1355 / 1360

页数：6

共 50 条

[21] A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis
Murano, Hiroki
Matsubara, Takumi
Takahashi, Ikuo
Hara, Masakazu
PLANT BIOTECHNOLOGY REPORTS, 2017, 11 (02) : 107 - 113
[22] Molecular cloning, characterization and expression analysis of heat shock protein 90 in albino northern snakehead Channa argus
Zhou, Aiguo
Xie, Shaolin
Wang, Zhenlu
Junaid, Muhammad
Fan, Lanfen
Wang, Chao
Ye, Qiao
Chen, Yanfeng
Pei, De-Sheng
Zou, Jixing
GENE, 2017, 626 : 173 - 181
[23] Heat shock protein 90 as a molecular target for cancer therapeutics
Isaacs, JS
Xu, WP
Neckers, L
CANCER CELL, 2003, 3 (03) : 213 - 217
[24] Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum
Duc-Cuong Bui
Yoonji Lee
Jae Yun Lim
Minmin Fu
Jin-Cheol Kim
Gyung Ja Choi
Hokyoung Son
Yin-Won Lee
Scientific Reports, 6
[25] Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum
Bui, Duc-Cuong
Lee, Yoonji
Lim, Jae Yun
Fu, Minmin
Kim, Jin-Cheol
Choi, Gyung Ja
Son, Hokyoung
Lee, Yin-Won
SCIENTIFIC REPORTS, 2016, 6
[26] Heat shock protein - Response
Matz, PG
Sharp, FR
JOURNAL OF NEUROSURGERY, 1997, 86 (01) : 172 - 172
[27] Phylogenetic analysis of Babesia gibsoni isolates of south India using apical membrane antigen, 50 kDa surface antigen, and 70 kDa heat shock protein genes
Deepa, Chundayil Kalarickal
Varghese, Anju
Bora, Christophe Angeline Felicia
Kumar, Karapparambu Gopalan Ajith
John, Lijo
Asaf, Muhasin
Chulliparambil, Sunanda
Ravindran, Reghu
EXPERIMENTAL PARASITOLOGY, 2023, 246
[28] The heat shock protein 90kD (Hsp90) modulates the heat shock response and cardioprotection in neonatal rat cardiomyocytes
Griffin, TM
Valdez, T
Mestril, R
CIRCULATION, 2002, 106 (19) : 313 - 313
[29] Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome
Anighoro, Andrew
Stumpfe, Dagmar
Heikamp, Kathrin
Beebe, Kristin
Neckers, Leonard M.
Bajorath, Jurgen
Rastelli, Giulio
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2015, 55 (03) : 676 - 686
[30] Exogenous expression of heat shock protein 90kDa retards the cell cycle and impairs the heat shock response
Zhao, C
Hashiguchi, A
Kondoh, K
Du, WL
Hata, J
Yamada, T
EXPERIMENTAL CELL RESEARCH, 2002, 275 (02) : 200 - 214

← 1 2 3 4 5 →