Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients

被引:194
作者
Miettunen, Paivi M. [1 ,2 ]
Narendran, Aru [2 ,3 ]
Jayanthan, Aarthi [2 ,3 ]
Behrens, Edward M. [4 ]
Cron, Randy Q. [5 ]
机构
[1] Alberta Childrens Prov Gen Hosp, Dept Pediat, Div Pediat Rheumatol, Calgary, AB T3B 6A8, Canada
[2] Univ Calgary, Dept Pediat, Calgary, AB T2N 1N4, Canada
[3] Div Pediat Oncol, Calgary, AB, Canada
[4] Childrens Hosp Philadelphia, Dept Pediat, Div Rheumatol, Philadelphia, PA USA
[5] Univ Alabama, Dept Pediat, Med Sch Birmingham, Childrens Hosp Alabama, Birmingham, AL USA
关键词
JUVENILE IDIOPATHIC ARTHRITIS; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; GUIDELINES; ANAKINRA;
D O I
10.1093/rheumatology/keq218
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:417 / 419
页数:3
相关论文
共 10 条
[1]  
Behrens EM, 2007, J RHEUMATOL, V34, P1133
[2]  
Behrens EM, 2006, J RHEUMATOL, V33, P2081
[3]  
Chen Hsin-Hsu, 2007, Journal of Microbiology Immunology and Infection, V40, P265
[4]   Macrophage Activation Syndrome Treated with Anakinra [J].
Durand, Madeleine ;
Troyanov, Yves ;
Laflamme, Pierre ;
Gregoire, Genevieve .
JOURNAL OF RHEUMATOLOGY, 2010, 37 (04) :879-881
[5]   HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis [J].
Henter, Jan-Inge ;
Horne, AnnaCarin ;
Arico, Maurizio ;
Egeler, R. Maarten ;
Filipovich, Alexandra H. ;
Imashuku, Shinsaku ;
Ladisch, Stephan ;
McClain, Ken ;
Webb, David ;
Winiarski, Jacek ;
Janka, Gritta .
PEDIATRIC BLOOD & CANCER, 2007, 48 (02) :124-131
[6]   Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation [J].
Henter, JI ;
Samuelsson-Horne, A ;
Aricò, M ;
Egeler, RM ;
Elinder, G ;
Filipovich, AH ;
Gadner, H ;
Imashuku, S ;
Komp, D ;
Ladisch, S ;
Webb, D ;
Janka, G .
BLOOD, 2002, 100 (07) :2367-2373
[7]   A case of macrophage activation syndrome successfully treated with anakinra [J].
Kelly, Alison ;
Ramanan, Athimalaipet V. .
NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2008, 4 (11) :615-620
[8]   Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade [J].
Pascual, V ;
Allantaz, F ;
Arce, E ;
Punaro, M ;
Banchereau, J .
JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (09) :1479-1486
[9]   Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis [J].
Ravelli, A ;
Magni-Manzoni, S ;
Pistorio, A ;
Besana, C ;
Foti, T ;
Ruperto, N ;
Viola, S ;
Martini, A .
JOURNAL OF PEDIATRICS, 2005, 146 (05) :598-604
[10]   Macrophage activation syndrome: a potentially fatal complication of rheumatic disorders [J].
Sawhney, S ;
Woo, P ;
Murray, KJ .
ARCHIVES OF DISEASE IN CHILDHOOD, 2001, 85 (05) :421-426