Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients

被引:193
作者
Miettunen, Paivi M. [1 ,2 ]
Narendran, Aru [2 ,3 ]
Jayanthan, Aarthi [2 ,3 ]
Behrens, Edward M. [4 ]
Cron, Randy Q. [5 ]
机构
[1] Alberta Childrens Prov Gen Hosp, Dept Pediat, Div Pediat Rheumatol, Calgary, AB T3B 6A8, Canada
[2] Univ Calgary, Dept Pediat, Calgary, AB T2N 1N4, Canada
[3] Div Pediat Oncol, Calgary, AB, Canada
[4] Childrens Hosp Philadelphia, Dept Pediat, Div Rheumatol, Philadelphia, PA USA
[5] Univ Alabama, Dept Pediat, Med Sch Birmingham, Childrens Hosp Alabama, Birmingham, AL USA
关键词
JUVENILE IDIOPATHIC ARTHRITIS; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; GUIDELINES; ANAKINRA;
D O I
10.1093/rheumatology/keq218
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:417 / 419
页数:3
相关论文
共 10 条
  • [1] Behrens EM, 2007, J RHEUMATOL, V34, P1133
  • [2] Behrens EM, 2006, J RHEUMATOL, V33, P2081
  • [3] Chen Hsin-Hsu, 2007, Journal of Microbiology Immunology and Infection, V40, P265
  • [4] Macrophage Activation Syndrome Treated with Anakinra
    Durand, Madeleine
    Troyanov, Yves
    Laflamme, Pierre
    Gregoire, Genevieve
    [J]. JOURNAL OF RHEUMATOLOGY, 2010, 37 (04) : 879 - 881
  • [5] HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
    Henter, Jan-Inge
    Horne, AnnaCarin
    Arico, Maurizio
    Egeler, R. Maarten
    Filipovich, Alexandra H.
    Imashuku, Shinsaku
    Ladisch, Stephan
    McClain, Ken
    Webb, David
    Winiarski, Jacek
    Janka, Gritta
    [J]. PEDIATRIC BLOOD & CANCER, 2007, 48 (02) : 124 - 131
  • [6] Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
    Henter, JI
    Samuelsson-Horne, A
    Aricò, M
    Egeler, RM
    Elinder, G
    Filipovich, AH
    Gadner, H
    Imashuku, S
    Komp, D
    Ladisch, S
    Webb, D
    Janka, G
    [J]. BLOOD, 2002, 100 (07) : 2367 - 2373
  • [7] A case of macrophage activation syndrome successfully treated with anakinra
    Kelly, Alison
    Ramanan, Athimalaipet V.
    [J]. NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2008, 4 (11): : 615 - 620
  • [8] Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    Pascual, V
    Allantaz, F
    Arce, E
    Punaro, M
    Banchereau, J
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (09) : 1479 - 1486
  • [9] Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    Ravelli, A
    Magni-Manzoni, S
    Pistorio, A
    Besana, C
    Foti, T
    Ruperto, N
    Viola, S
    Martini, A
    [J]. JOURNAL OF PEDIATRICS, 2005, 146 (05) : 598 - 604
  • [10] Macrophage activation syndrome: a potentially fatal complication of rheumatic disorders
    Sawhney, S
    Woo, P
    Murray, KJ
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2001, 85 (05) : 421 - 426