Electrochemical Aptasensor for Detection of Ochratoxin A

被引：2

作者：

Shan, Yanqun ^{[1
]}

Wang, Xiaoying ^{[1
]}

机构：

[1] Southeast Univ, Sch Publ Hlth, Key Lab Environm Med Engn, Minist Educ, Nanjing 210009, Jiangsu, Peoples R China

来源：

PROGRESS IN CHEMISTRY | 2018年 / 30卷 / 06期

基金：

中国国家自然科学基金;

关键词：

ochratoxin A; detection technology; aptamer; electrochemical aptasensor; PERFORMANCE LIQUID-CHROMATOGRAPHY; IMPEDIMETRIC APTASENSOR; ULTRASENSITIVE DETECTION; DNA APTAMER; SENSITIVE DETECTION; GOLD NANOPARTICLES; SENSING PLATFORM; COCOA BEANS; BIOSENSOR; SIGNAL;

D O I：

10.7536/PC171022

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ochratoxin A (OTA) is a toxic secondary metabolite of small molecular weight mainly produced by Aspergillus and Penicillium species, which are widely found in food, agricultural products and animal feed. It has strong hepatotoxicity, nephrotoxicity, teratogenic and mutagenic effects, and is also a class. B carcinogens. In view of OTA's universality and harmfulness, the present situation of the commonly used detection methods of OTA is summarized and compared in this paper. Specifically, the application of new electrochemical aptasensor in OTA detection is mainly described. OTA electrochemical aptasensors are divided into three categories: configuration transformation type, affinity type and hybrid type. Their respective principles, characteristics and the latest research progress are discussed in detail. Furthermore, the summary of the future directions and the potential applications are given, which provides reference for the further research and application of OTA.

引用

页码：797 / 808

页数：12

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