Frequency of West Nile Virus Infection in Iranian Blood Donors

被引：18

作者：

Aghaie, Afsaneh ^{[1
]}

Aaskov, John ^{[2
]}

Chinikar, Sadegh ^{[3
]}

Niedrig, Matthias ^{[4
]}

Banazadeh, Soudabeh ^{[5
]}

Mohammadpour, Hashem Khorsand ^{[6
]}

机构：

[1] High Inst Res & Educ Transfus Med, Blood Transfus Res Ctr, POB 14665-1157, Tehran, Iran

[2] Queensland Univ Technol, Brisbane, Qld, Australia

[3] Pasteur Inst Iran, Arboviruses & VHFs Lab, Tehran, Iran

[4] Robert Koch Inst, Berlin, Germany

[5] Iranian Blood Res & Fractionat Holding Co, Qual Assurance, Tehran, Iran

[6] Iranian Blood Res & Fractionat Holding Co, Res Ctr, Tehran, Iran

来源：

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION | 2016年 / 32卷 / 03期

关键词：

West Nile virus (WNV); Blood donor; Iran; Donor selection; Epidemiology; Enzyme linked immune sorbent assay (ELISA); Immunoflouorescence assay (IFA);

D O I：

10.1007/s12288-015-0567-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.

引用

页码：343 / 346

页数：4

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