One-step synthesis of magnetic hollow mesoporous silica (MHMS) nanospheres for drug delivery nanosystems via electrostatic self-assembly templated approach

被引:41
作者
Liu, Fang [1 ,4 ]
Wang, Jingnan [2 ]
Cao, Qingyun [3 ]
Deng, Haidong [1 ]
Shao, Guang [4 ]
Deng, David Y. B. [2 ]
Zhou, Wuyi [1 ]
机构
[1] South China Agr Univ, Inst Biomaterial, Dept Appl Chem, Coll Sci, Guangzhou 510642, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 1, Res Ctr Translat Med, Guangzhou 510080, Guangdong, Peoples R China
[3] South China Agr Univ, Coll Anim Sci, Guangzhou 510642, Guangdong, Peoples R China
[4] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
关键词
NANOPARTICLES; CARRIER; SHELL; CORE; MICROSPHERES; THERAPY;
D O I
10.1039/c4cc08914f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this work, yolk-shell structured magnetic hollow mesoporous silica (MHMS) nanospheres with controllable magnetic responsibility, high specific surface area, a huge cavity and ink-bottle type mesopores were successfully synthesized in one-step by an electrostatic self-assembly templated approach. The obtained MHMS nanospheres exhibited low cytotoxicity, excellent biocompatibility and potential application in the biomedical field.
引用
收藏
页码:2357 / 2360
页数:4
相关论文
共 22 条
[1]  
Cho MH, 2012, NAT MATER, V11, P1038, DOI [10.1038/NMAT3430, 10.1038/nmat3430]
[2]   Hollow spherical mesoporous phosphosilicate nanoparticles as a delivery vehicle for an antibiotic drug [J].
Das, Swapan K. ;
Bhunia, Manas K. ;
Chakraborty, Debrup ;
Khuda-Bukhsh, Anisur Rahman ;
Bhaumik, Asim .
CHEMICAL COMMUNICATIONS, 2012, 48 (23) :2891-2893
[3]   Superparamagnetic high-magnetization microspheres with an Fe3O4@SiO2 core and perpendicularly aligned mesoporous SiO2 shell for removal of microcystins [J].
Deng, Yonghui ;
Qi, Dawei ;
Deng, Chunhui ;
Zhang, Xiangmin ;
Zhao, Dongyuan .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (01) :28-+
[4]   Multifunctional Uniform Nanoparticles Composed of a Magnetite Nanocrystal Core and a Mesoporous Silica Shell for Magnetic Resonance and Fluorescence Imaging and for Drug Delivery [J].
Kim, Jaeyun ;
Kim, Hoe Suk ;
Lee, Nohyun ;
Kim, Taeho ;
Kim, Hyoungsu ;
Yu, Taekyung ;
Song, In Chan ;
Moon, Woo Kyung ;
Hyeon, Taeghwan .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (44) :8438-8441
[5]   Light penetration properties of NIR radiation in fruit with respect to non-destructive quality assessment [J].
Lammertyn, J ;
Peirs, A ;
De Baerdemaeker, J ;
Nicolaï, B .
POSTHARVEST BIOLOGY AND TECHNOLOGY, 2000, 18 (02) :121-132
[6]   Synthesis and Characterization of Biocompatible and Size-Tunable Multifunctional Porous Silica Nanoparticles [J].
Lin, Yu-Shen ;
Haynes, Christy L. .
CHEMISTRY OF MATERIALS, 2009, 21 (17) :3979-3986
[7]   High-efficiency loading in small mesopores (2-3 nm) forming a matrix type controlled drug delivery nanosystem [J].
Liu, Fang ;
Zhang, Hongwu ;
Cao, Qingyun ;
Xiang, Xianhong ;
Wang, Liqin ;
He, Ting ;
Liu, Wei ;
Fang, Yueping ;
Deng, David Y. B. ;
Zhou, Wuyi .
RSC ADVANCES, 2014, 4 (17) :8918-8921
[8]  
Liu Y., 1999, J FUNCT BIOMATER, V1, P24
[9]   Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia [J].
Lu, Feng ;
Popa, Adriana ;
Zhou, Shiwei ;
Zhu, Jun-Jie ;
Samia, Anna Cristina S. .
CHEMICAL COMMUNICATIONS, 2013, 49 (97) :11436-11438
[10]   Synthesis of mesoporous hollow silica nanospheres using polymeric micelles as template and their application as a drug-delivery carrier [J].
Sasidharan, Manickam ;
Zenibana, Haruna ;
Nandi, Mahasweta ;
Bhaumik, Asim ;
Nakashima, Kenichi .
DALTON TRANSACTIONS, 2013, 42 (37) :13381-13389