Triazolylidene Ligands Allow Cobalt-Catalyzed C-H/C-O Alkenylations at Ambient Temperature

被引：14

作者：

Sauermann, Nicolas ^{[1
]}

Loup, Joachim ^{[1
]}

Kootz, Darius ^{[2
]}

Yatham, V. Reddy ^{[2
]}

Berkessel, Albrecht ^{[2
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Georg August Univ, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

[2] Univ Cologne, Organ Chem, Dept Chem, Greinstr 4, D-50939 Cologne, Germany

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 15期

关键词：

carbene; cobalt; C-H activation; C-O functionalization; triazolylidene; H BOND ACTIVATION; CROSS-COUPLING REACTIONS; SECONDARY ALKYL-HALIDES; SELECTIVE FUNCTIONALIZATION; OLEFIN METATHESIS; AROMATIC IMINES; STABLE CARBENE; ARYLATIONS; COMPLEXES; PHOSPHATES;

D O I：

10.1055/s-0036-1590471

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct alkenylation through C-H/C-O cleavage was accomplished under mild reaction conditions by cobalt catalysts derived from novel triazolylidene ligands. The most effective ligand is characterized by sterically demanding substituents on the 1,4-N-atoms of the triazolylidene neighboring the carbene center. The C-H alkenylations proved viable with alkenyl acetates, carbamates, carbonates and phosphates. For acyclic electrophiles, diastereoconvergent C-O functionalizations were observed.

引用

页码：3476 / 3484

页数：9

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