Electrogenerated base-promoted synthesis and antimicrobial activity of 2-(1,3-dithian-2-ylidene)-2-arylacetonitrile and 2-(1,3-dithiolan-2-ylidene)-2-arylacetonitrile

被引：7
|
作者：
Hamrouni, Kaouthar [1 ]
Saied, Taieb [1 ,2 ]
El Abed, Nariman [3 ]
Ahmed, Sami Ben Hadj [3 ]
Boujlel, Khaled [1 ]
Ben Khoud, Mohamed Lamine [1 ]
机构：
[1] Univ Tunis El Manar, Fac Sci Tunis, Lab Chim Analyt & Electrochim, Tunis, Tunisia
[2] Inst Natl Sci Appl & Technol, Dept Chim & Biol Appl, Tunis, Tunisia
[3] Univ Carthage, Inst Natl Sci Appl & Technol, Lab Prot & Mol Bioact Ingn, Ctr Urbain Nord, Tunis, Tunisia
来源：
JOURNAL OF SULFUR CHEMISTRY | 2015年 / 36卷 / 02期
关键词：
antimicrobial activity; carbone disulfur; 2-(1,3-dithian-2-ylidene)-2-arylacetonitrile; 2-(1,3-dithiol-2-ylidene)-2-arylacetonitrile; anion EGBs; CYANOMETHYL ANION; DERIVATIVES; OXAZOLIDIN-2-ONES; ESTERS; AMINES;
D O I：
10.1080/17415993.2015.1005620
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The new preparation of 2-(1,3-dithian-2-ylidene)-2-arylacetonitrile and 2-(1,3-dithiol-2-ylidene)-2-arylacetonitrile is described. The electrogenerated cyanomethyl base/anion obtained from the electroreduction of acetonitrile promotes reactions between arylacetonitrile, carbon disulfide and 1-bromo-3-chloropropane or 1,2-dibromoethane. Obtained products have been identified according to their spectroscopic data (IR and H-1 NMR and C-13 NMR) and elemental analysis. The possible antibacterial activities of some of these compounds were investigated. Promising results were found against few types of bacteria.
引用
收藏
页码：196 / 206
页数：11
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