Postoperative AKI

被引：47
作者：
Boyer, Naomi [1 ,2 ]
Eldridge, Jack [3 ,4 ]
Prowle, John R. [3 ,4 ]
Forni, Lui G. [1 ,2 ,5 ,6 ]
机构：
[1] Royal Surrey Hosp, Dept Crit Care, Guildford, England
[2] Royal Surrey Hosp, SPACeR Grp Surrey Perioperat Anaesthesia & Crit Ca, Guildford, England
[3] Queen Mary Univ London, William Harvey Res Inst, London, England
[4] Royal London Hosp Barts Hlth Natl Hlth Serv Trust, Adult Crit Care Unit, London, England
[5] Univ Surrey, Fac Hlth Sci, Dept Clin & Expt Med, Guildford, England
[6] Royal Surrey Hosp, Dept Crit Care, Egerton Rd, Guildford GU27XX, Surrey, England
来源：
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2022年 / 17卷 / 10期
关键词：
Critical Care Nephrology and Acute Kidney Injury Series; acute kidney injury; perioperative; postoperative; surgery; biomarkers; kidney replacement therapy; ACUTE KIDNEY INJURY; IATROGENIC URETERAL INJURY; CARDIAC-SURGERY; NONCARDIAC SURGERY; MAJOR SURGERY; URINE OUTPUT; RISK-FACTORS; CREATININE; OUTCOMES; MANAGEMENT;
D O I：
10.2215/CJN.16541221
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Postoperative AKI is a common complication of major surgery and is associated with significant morbidity and mortality. The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine output. However, such conventional diagnostic criteria may be inaccurate in the postoperative period, suggesting a potential to refine diagnosis by application of novel diagnostic biomarkers. Risk factors for the development of postoperative AKI can be thought of in terms of preoperative, intraoperative, and postoperative factors and, as such, represent areas that may be targeted perioperatively to minimize the risk of AKI. The treatment of postoperative AKI remains predominantly supportive, although application of management bundles may translate into improved outcomes.
引用
收藏
页码：1535 / 1545
页数：11
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