Effect of Endomorphin-1 on Contractile Activity of Rat Mesenteric Lymphatic Vessels

被引：1
|
作者：
Nechaykina, O. V. [1 ]
Petunov, S. G. [1 ]
机构：
[1] Fed Med Biol Agcy Russia, Res Inst Hyg Occupat Pathol & Human Ecol, Kuzmolovsky, Leningrad Regio, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2019年 / 168卷 / 01期
关键词：
isolated lymphatic vessels; endomorphin-1; opioid receptors; MU-OPIOID RECEPTOR; AGONISTS;
D O I：
10.1007/s10517-019-04645-3
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied the effect of endomorphin-1 on isolated mesenteric lymphatic vessels in rats. It was found that endomorphin-1 caused a dose-dependent increase in the contractile activity of lymphangions, which was associated with stimulation of intracellular calcium depots. The observed effect of endomorphin-1 in isolated lymphatic vessels has a complex mechanism; it depends on the concentration of the applied peptide and is probably determined by its interaction with non-opioid receptors.
引用
收藏
页码：55 / 57
页数：3
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