Protein-protein interactions in intracellular membrane fusion

被引：23
|
作者：
Misura, KMS [1 ]
May, AP
Weis, WI
机构：
[1] Stanford Univ, Sch Med, Dept Biol Struct, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Cellular & Mol Physiol, Stanford, CA 94305 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2000年 / 10卷 / 06期
关键词：
D O I：
10.1016/S0959-440X(00)00151-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The fusion of intracellular vesicles with their target membranes is an essential feature of the compartmental structure of eukaryotic cells. This process requires proteins that dictate the targeting of a vesicle to the correct cellular location, mediate bilayer fusion and, in some systems, regulate the precise time at which fusion occurs. Recent biophysical and structural studies of these proteins have begun to provide a foundation for understanding their functions at a molecular level.
引用
收藏
页码：662 / 671
页数：10
相关论文
共 50 条
  • [41] Peptide-encoding gene transfer to modulate intracellular protein-protein interactions
    Taya, Toshihiko
    Kami, Daisuke
    Teruyama, Fumiya
    Matoba, Satoaki
    Gojo, Satoshi
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2024, 32
  • [42] α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells
    Checco, James W.
    Lee, Erinna F.
    Evangelista, Marco
    Sleebs, Nerida J.
    Rogers, Kelly
    Pettikiriarachchi, Anne
    Kershaw, Nadia J.
    Eddinger, Geoffrey A.
    Belair, David G.
    Wilson, Julia L.
    Eller, Chelcie H.
    Raines, Ronald T.
    Murphy, William L.
    Smith, Brian J.
    Gellman, Samuel H.
    Fairlie, W. Douglas
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (35) : 11365 - 11375
  • [43] Predicting lncRNA-Protein Interactions Based on Protein-Protein Similarity Network Fusion
    Zheng, Xiaoxiang
    Tian, Kai
    Wang, Yang
    Guan, Jihong
    Zhou, Shuigeng
    BIOINFORMATICS RESEARCH AND APPLICATIONS, ISBRA 2016, 2016, 9683 : 321 - 322
  • [44] Dissecting protein-protein interactions through oxidative crosslinking of a GGH-fusion protein
    Brown, KC
    Yu, ZH
    Burlingame, A
    Craik, C
    FASEB JOURNAL, 1997, 11 (09): : A1325 - A1325
  • [45] Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides
    Qian, Ziqing
    Dougherty, Patrick G.
    Pei, Dehua
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2017, 38 : 80 - 86
  • [46] Assessing the cellular toxicity of peptide inhibitors of intracellular protein-protein interactions by microinjection
    Reddiar, Sanjeevini Babu
    Al-Wassiti, Hareth
    Pouton, Colin W.
    Nowell, Cameron J.
    Matthews, Macgregor A.
    Rahman, Arfatur
    Barlow, Nicholas
    Norton, Raymond S.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 29
  • [47] α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells
    20153701269407
    Gellman, Samuel H. (gellman@chem.wisc.edu), 1600, American Chemical Society (137):
  • [48] Application of a green fluorescent fusion protein to study protein-protein interactions by electrophoretic methods
    Kiessig, S
    Reissmann, J
    Rascher, C
    Küllertz, G
    Fischer, A
    Thunecke, F
    ELECTROPHORESIS, 2001, 22 (07) : 1428 - 1435
  • [49] Protein-protein interactions regulate the activity of Adipose Triglyceride Lipase in intracellular lipolysis
    Kulminskaya, Natalia
    Oberer, Monika
    BIOCHIMIE, 2020, 169 : 62 - 68
  • [50] Protein-protein interactions in intracellular Ca2+-release channel function
    Mackrill, JJ
    BIOCHEMICAL JOURNAL, 1999, 337 : 345 - 361
12345