Feasibility of enzyme biosensors based on gold nanowires

被引:21
作者
Cusma, A.
Curulli, A.
Zane, D.
Kaciulis, S.
Padeletti, G.
机构
[1] CNR, Inst Study Nanostruct Mat ISMN, Montelibretti Res Div, I-00016 Monterotondo, Rome, Italy
[2] CNR, Inst Study Nanostruct Mat ISMN, Rome Res Div 2, I-00016 Rome, Italy
来源
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2007年 / 27卷 / 5-8期
关键词
gold nanowires; template synthesis; electroless plating-deposition; atomic force microscopy; biosensors;
D O I
10.1016/j.msec.2006.09.035
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Gold nanowires were prepared by electroless deposition within the pores of polycarbonate particle track-etched membranes (PTM). Glucose oxidase was deposited onto the nanowires using self-assembling monolayer as anchor layers for the enzyme molecules. AFM characterization was performed before and after the immobilization of the enzyme. Finally cyclic voltammetry was performed for different enzymes to test the applicability of gold nanowires as biosensors. The AFM measurements proved the immobilization of the enzyme while the electrochemical characterization showed that the presence of nanowired substrates greatly enhances the electrical response of the biosensor. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:1158 / 1161
页数:4
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